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The medial VSMC is the organizer of the inwardly directed angiogenic response arising from the adventitia by overexpressing vascular endothelial growth factor in response to lipid-stimulated ...

Cardiovascular Research, REVIEWS: SPOTLIGHT ON SMOOTH MUSCLE CELLS AND VASCULAR DISEASES, Patrick Lacolley, Véronique Regnault, Antonino Nicoletti, Zhenlin Li, Jean-Baptiste Michel

Date : 15/07/2012 Item size : 569256 bytes

Through the metabolic breakdown of ingested nutrients, subsequent production of the electron carriers NADH and FADH2 in the citric acid cycle and the transfer of electrons through the electron ...

Cardiovascular Research, Review, Alexander W. Lohman, Marie Billaud, Brant E. Isakson

Date : 01/08/2012 Item size : 637634 bytes

The development and structure of blood vessels are highly adapted to haemodynamic forces, such as shear stress, cyclic stretch, and circumferential wall stress, generated by the conductance of ...

Cardiovascular Research, SPOTLIGHT REVIEWS: SPOTLIGHT ON BIOMECHANICAL FACTORS IN CARDIOVASCULAR DISEASE, Peter Neth, Maliheh Nazari-Jahantigh, Andreas Schober, Christian Weber

Date : 15/07/2013 Item size : 558042 bytes

Abstract Objective: Promoting angiogenesis may be an effective treatment for patients with diffuse peripheral vascular disease. Conclusion: Administration of estrogen promotes angiogenesis and ...

Cardiovascular Research, Original Article, Zenon S. Kyriakides, Pantelis Petinakis, Loukas Kaklamanis, Eftihia Sbarouni, Panagiotis Karayannakos, Dimitrios Iliopoulos, Ismene Dontas, Dimitrios Th. ...

Date : 16/02/2001 Item size : 236593 bytes

In essential hypertension some evidence for decreased systemic and skin activity of 11β-HSD1 and/or 11β-HSD2 has been found, while renal activity of both isozymes appears to be normal. ...

Cardiovascular Research, Review, Stan H.M. van Uum, Ad R.M.M. Hermus, Paul Smits, Theo Thien, Jacques W.M. Lenders

Date : 01/04/1998 Item size : 477532 bytes

Abstract Objective: We have shown previously that there is a relative nitric oxide deficiency at the level of vascular endothelium in the stroke-prone spontaneously hypertensive rat (SHRSP), a model ...

Cardiovascular Research, Original Article, M.Yvonne Alexander, M.Julia Brosnan, Carlene A Hamilton, Paul Downie, Alison M Devlin, Fiona Dowell, William Martin, Howard M Prentice, Timothy ...

Date : 15/08/1999 Item size : 290659 bytes

Abstract Aims Vascular disease states are associated with endothelial dysfunction and increased production of reactive oxygen species derived from NADPH oxidases. Increased endothelial superoxide ...

Cardiovascular Research, Original Article, Gillian Douglas, Jennifer K. Bendall, Mark J. Crabtree, Amy L. Tatham, Emma E. Carter, Ashley B. Hale, Keith M. Channon

Date : 01/04/2012 Item size : 270141 bytes

Introduction Non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) have been used in clinical practice for more than a century and are among the most widely used drugs worldwide for the ...

European Heart Journal - Cardiovascular Pharmacotherapy, REVIEWS, Morten Schmidt, Morten Lamberts, Anne-Marie Schjerning Olsen, Emil Fosbøll, Alexander Niessner, Juan Tamargo, Giuseppe Rosano, ...

Date : 01/04/2016 Item size : 461588 bytes

Six known IL-17 family members (IL-17AF), including the prototypical IL-17A (also known as IL-17), exert potent pro-inflammatory effects and are produced by a myriad of immune cells.13 Once thought ...

Cardiovascular Research, Vascular biology, Hoanglan Nguyen, Valorie L. Chiasson, Piyali Chatterjee, Shelley E. Kopriva, Kristina J. Young, Brett M. Mitchell

Date : 15/03/2013 Item size : 350371 bytes

ETA receptors on vascular smooth muscle mediate vasoconstriction,1 as well as mitogenesis,2 reactive oxygen species production, and adhesion molecule expression,3,4 while those on leucocytes mediate ...

Cardiovascular Research, Original Article, Nicholas S. Kirkby, Karolina M. Duthie, Eileen Miller, Yuri V. Kotelevtsev, Alan J. Bagnall, David J. Webb, Patrick W.F. Hadoke

Date : 01/07/2012 Item size : 284129 bytes