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Adverse cardiovascular prognosis of obesity is linked to: endothelial dysfunction, abnormal left ventricular geometry, systolic and diastolic left ventricular dysfunction, heart failure, increased ...

Date : 08/07/2016

Here, we focus on the role of miRNA in vascular inflammation and remodelling associated with acute vascular injury (vein graft disease, angioplasty restenosis, and in-stent restenosis) as well as in ...

Cardiovascular Research, REVIEWS: FOCUS ON MICRORNA IN CARDIOVASCULAR BIOLOGY AND DISEASE, Robert A. McDonald, Akiko Hata, Margaret R. MacLean, Nicholas W. Morrell, Andrew H. Baker

Date : 15/03/2012 Item size : 449433 bytes

Fig. 1 (A) Age-dependent incidence of coronary artery disease (CAD) in men and women (Framingham Heart Study). The Nurses' Health Study reports an increased risk of CVD in women with bilateral ...

Cardiovascular Research, Review, Raghvendra K. Dubey, Bruno Imthurn, Matthias Barton, Edwin K. Jackson

Date : 01/05/2005 Item size : 499621 bytes

Abstract Objective: We have shown previously that there is a relative nitric oxide deficiency at the level of vascular endothelium in the stroke-prone spontaneously hypertensive rat (SHRSP), a model ...

Cardiovascular Research, Original Article, M.Yvonne Alexander, M.Julia Brosnan, Carlene A Hamilton, Paul Downie, Alison M Devlin, Fiona Dowell, William Martin, Howard M Prentice, Timothy ...

Date : 15/08/1999 Item size : 290659 bytes

In these studies, the prevalence of this subgroup, termed diastolic heart failure (DHF), is up to 55% in patients hospitalized or discharged with a diagnosis of congestive heart failure.2–4 ...

European Journal of Heart Failure, Edelmann, Frank, Schmidt, Albrecht G., Gelbrich, Götz, Binder, Lutz, Herrmann‐Lingen, Christoph, Halle, Martin, Hasenfuss, Gerd, Wachter, Rolf, Pieske, Burkert

Date : 01/08/2010 Item size : 207047 bytes

Abstract Aims Vascular disease states are associated with endothelial dysfunction and increased production of reactive oxygen species derived from NADPH oxidases. Increased endothelial superoxide ...

Cardiovascular Research, Original Article, Gillian Douglas, Jennifer K. Bendall, Mark J. Crabtree, Amy L. Tatham, Emma E. Carter, Ashley B. Hale, Keith M. Channon

Date : 01/04/2012 Item size : 270141 bytes

Abstract Endothelial production of nitric oxide (nitrogen monoxide, NO) has become a major research area in vascular biology. The aim of this review is to examine the cellular and molecular ...

Cardiovascular Research, Review, Michael T Gewaltig, Georg Kojda

Date : 01/08/2002 Item size : 486616 bytes

Six known IL-17 family members (IL-17AF), including the prototypical IL-17A (also known as IL-17), exert potent pro-inflammatory effects and are produced by a myriad of immune cells.13 Once thought ...

Cardiovascular Research, Vascular biology, Hoanglan Nguyen, Valorie L. Chiasson, Piyali Chatterjee, Shelley E. Kopriva, Kristina J. Young, Brett M. Mitchell

Date : 15/03/2013 Item size : 350371 bytes

Abstract Aldosterone is well recognized as a cause of sodium reabsorption, water retention, and potassium and magnesium loss; however, it also produces a variety of other actions that lead to ...

Cardiovascular Research, Review, Allan D Struthers, Thomas M MacDonald

Date : 01/03/2004 Item size : 333477 bytes

Conclusion: Cerivastatin, but not gemfibrozil significantly reduces RLP-C increase after an oral fat load in combination with a reversal of fat-load induced endothelial ...

Cardiovascular Research, Original Article, Hanneke W Wilmink, Marcel B Twickler, Jan Dirk Banga, Geesje M Dallinga-Thie, Hans Eeltink, D.Willem Erkelens, Ton J Rabelink, Erik S Stroes

Date : 01/06/2001 Item size : 242418 bytes