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Role of neuronal nitric oxide synthase in lipopolysaccharide-induced tumor necrosis factor-alpha expression in neonatal mouse cardiomyocytes Calcium in turn modulates extracellular signal-related ...

Cardiovascular Research, Original Article, Nicola Geoghegan-Morphet, Dylan Burger, Xiangru Lu, Venkatachalem Sathish, Tianqing Peng, Stephen M. Sims, Qingping Feng

Date : 15/07/2007 Item size : 270277 bytes

Methods and results In cultured neonatal mouse cardiomyocytes, deficiency of JNK1 or selective inhibition of JNK1 signalling by over-expression of a dominant negative mutant of JNK1 enhanced ...

Cardiovascular Research, Original Article, Tianqing Peng, Ting Zhang, Xiangru Lu, Qingping Feng

Date : 01/03/2009 Item size : 315319 bytes

In adults, EPO is produced primarily in the kidney via an oxygen-sensing mechanism and stimulates erythroid progenitors in the bone marrow to increase red blood cell mass. The therapeutic relevance ...

Cardiovascular Research, Editorial, Qingping Feng

Date : 01/09/2006 Item size : 169639 bytes

To investigate the role of PLCγ1 in endotoxemia in vivo, wild-type and heterozygous PLCγ1 knockout (PLCγ1+/ mice were pre-treated with either U73122, or its inactive analog U73343, or ...

Cardiovascular Research, Original Article, Tianqing Peng, E Shen, Jue Fan, Yan Zhang, J. Malcolm O. Arnold, Qingping Feng

Date : 01/04/2008

Abstract Objectives: The role of p38 mitogen-activated protein kinase (MAPK) activation in lipopolysaccharide (LPS)-induced myocardial dysfunction has not been clearly defined. TNF-α mRNA and ...

Cardiovascular Research, Original Article, Tianqing Peng, Xiangru Lu, Ming Lei, Gordon W Moe, Qingping Feng

Date : 01/10/2003

MKP1 attenuates ERK1/2 and p38 activation, inhibits myocardial TNF-α expression, and improves cardiac function in endotoxemia. [...]MKP1 represents an important negative feedback mechanism ...

Cardiovascular Research, Original Article, Ting Zhang, Xiangru Lu, Paul Arnold, Yin Liu, Reshma Baliga, Hong Huang, John Anthony Bauer, Yusen Liu, Qingping Feng

Date : 01/03/2012