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14:00 P4646 Increasing the efficacy of myocardial gene therapy with an intra-aortic balloon pump in a large animal model of heart failure Dennis LADAGE (Cologne, DE) 14:00 P4647 Influence of ...

Poster session 6: The many facets of regeneration

Date : 30/08/2011 Item size : 139444 bytes

AMPK is an emerging central sensor and regulator in cellular energy and nutrient signalling.5,6 The kinase is activated by numerous stimuli, mainly cellular energy stress during physiological ...

Cardiovascular Research, Original Article, Séverine Gratia, Laurence Kay, Lucia Potenza, Amal Seffouh, Valérie Novel-Chaté, Coralie Schnebelen, Piero Sestili, Uwe Schlattner, Malgorzata ...

Date : 01/08/2012 Item size : 350279 bytes

Role of Ca2+/calmodulin-dependent protein kinase II in cardiac hypertrophy and heart failure Abstract Ca2+/calmodulin-dependent protein kinase II (CaMKII), a critical transducer of Ca2+ signaling, ...

Cardiovascular Research, Review, Tong Zhang, Joan Heller Brown

Date : 15/08/2004 Item size : 465186 bytes

Introduction Patients with diabetes mellitus (DM) have an increased risk of coronary heart disease, and cardiovascular complications are responsible for the majority of diabetes-related deaths.1 In ...

Cardiovascular Research, ORIGINAL ARTICLES: SPOTLIGHT ON REDUCING MYOCARDIAL ISCHAEMIA/REPERFUSION INJURY, Tao Rui, Jinchao Zhang, Xuemei Xu, Yongwei Yao, Raymond Kao, Claudio M. Martin

Date : 01/05/2012 Item size : 272777 bytes

ReviewAuthors Chaanine Antoine H., Cardiovascular Research Center, Mount Sinai School of Medicine, New York, NY, USASearch for more papers by this author Hajjar Roger J. Corresponding ...

European Journal of Heart Failure, Chaanine, Antoine H., Hajjar, Roger J.

Date : 01/08/2011 Item size : 162603 bytes

Methods and results In cultured neonatal mouse cardiomyocytes, deficiency of JNK1 or selective inhibition of JNK1 signalling by over-expression of a dominant negative mutant of JNK1 enhanced ...

Cardiovascular Research, Original Article, Tianqing Peng, Ting Zhang, Xiangru Lu, Qingping Feng

Date : 01/03/2009 Item size : 315319 bytes

A reduction of this gradient has been implicated in a variety of pathologies including ischaemia/reperfusion,1,2 hypertrophy, and heart failure (HF).35 In hypertrophy and HF, many aspects of ...

Cardiovascular Research, Cardiac biology and remodelling, Andrii Boguslavskyi, Davor Pavlovic, Karen Aughton, James E. Clark, Jacqueline Howie, William Fuller, Michael J. Shattock

Date : 01/10/2014 Item size : 304021 bytes

Recap on NOS distribution and function in cardiovascular tissues Nitric oxide (NO) is a key universal signalling molecule in the cardiovascular system, acting on both acute and more chronic ...

Cardiovascular Research, REVIEWS: SPOTLIGHT ON REDUCING MYOCARDIAL ISCHAEMIA/REPERFUSION INJURY, Boris Manoury, Virginie Montiel, Jean-Luc Balligand

Date : 01/05/2012 Item size : 553690 bytes

Abstract Objective: N, N-Dimethylsphingosine (DMS) is recognized as an inhibitor of sphingosine kinase (SphK), a key enzyme responsible for the formation of sphingosine-1-phosphate (S1P). Methods In ...

Cardiovascular Research, Original Article, Zhu-Qiu Jin, Joel S. Karliner

Date : 01/09/2006 Item size : 311224 bytes

Understanding the signaling mechanisms of these receptors in the context of the heart is likely to provide a better therapeutic approach towards treatment of heart failure. Introduction Activation ...

Cardiovascular Research, Review, Liza Barki-Harrington, Cinzia Perrino, Howard A Rockman

Date : 15/08/2004 Item size : 572672 bytes