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Previous studies have demonstrated protective role of AMP-activated protein kinase (AMPK) genes in regulating atherosclerosis and hypertension. Aim of the present study was to identify role of LASS5 ...

Archives of the Turkish Society of Cardiology, 莖ban, Neslihan, Gl� Geyik, Filiz, Y齦d齬齧, 謟lem, Erginel 躰altuna, Nihan

Date : 02/01/2019 Item size : 26337 bytes

Considering that CVD preventive medications improve vascular outcomes in less than half of patients (often relative risk reductions range from 12% to 20% compared with placebo), precision medicine ...

European Heart Journal, Costantino, Sarah, Libby, Peter, Kishore, Raj, Tardif, Jean-Claude, El-Osta, Assam, Paneni, Francesco

Date : 14/12/2018 Item size : 683954 bytes

If not promptly recycled, 5OP can alter tissue redox conditions, as shown in the rodent brain,3 cardiomyocytes,4 and human derived myocardial tissue.4 Forced OPLAH expression in mice with myocardial ...

Cardiovascular Research, Sourdon, Joevin, Keceli, Gizem, Lindsey, Merry L, Paolocci, Nazareno

Date : 01/12/2018 Item size : 178226 bytes

Abstract Aims Immune cell function involves energy-dependent processes including growth, proliferation, and cytokine production. Since the AMP-activated protein kinase (AMPK) is a crucial regulator ...

Cardiovascular Research, Jansen, Thomas, Kröller-Schön, Swenja, Schönfelder, Tanja, Foretz, Marc, Viollet, Benoit, Daiber, Andreas, Oelze, Matthias, Brandt, Moritz, Steven, Sebastian, ...

Date : 01/12/2018 Item size : 349528 bytes

In cancers, Jumonji family members have been often found up-regulated and their inhibition by a small molecule called JIB-04, which is pan-selective inhibitor, determined produced anticancer ...

Cardiovascular Research, Mongelli, Alessia, Gaetano, Carlo

Date : 01/12/2018 Item size : 139165 bytes

Jane Freedman, MD is the Edward Budnitz Professor of Medicine at the University of Massachusetts Medical School and attends in the Division of Cardiology. Jane Freedman graduated from both Yale ...

European Heart Journal

Date : 07/11/2018 Item size : 100641 bytes

In this non-systematic review of the literature, we first present the definition of miRNAs and their action at the cellular level. Despite the complexity and challenges, it is crucial to identify ...

Date : 01/11/2018 Item size : 39931 bytes

Methods and results In Fibulin-4R/R mice, the extracellular matrix protein Fibulin-4 is 4-fold reduced, resulting in progressive ascending aneurysm formation and early death around 3 months of ...

Cardiovascular Research, van der Pluijm, Ingrid, Burger, Joyce, van Heijningen, Paula M, IJpma, Arne, van Vliet, Nicole, Milanese, Chiara, Schoonderwoerd, Kees, Sluiter, Willem, Ringuette, ...

Date : 01/11/2018 Item size : 517708 bytes

The HCA aims to describe and define the complete cellular landscape of the human body ( By analogy to the Human Genome Project, the HCA aims to map cells of the ...

Cardiovascular Research, Noseda, Michela, Harding, Sian Elizabeth

Date : 01/10/2018 Item size : 166060 bytes

Amongst numerous awards, she received the Liselotte-Becht research award (2017) and the Oskar-Lapp research award (2016) of the German Cardiac Society, the best moderated poster award of the ESC ...

Cardiovascular Research, Schmidt, Constanze

Date : 01/10/2018 Item size : 140170 bytes