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Abstract Nitric oxide (NO) generated constitutively within the heart has long been known to influence myocardial function; however, the precise nature of these effects has been controversial at least ...

Cardiovascular Research, Review, Mike Seddon, Ajay M. Shah, Barbara Casadei

Date : 15/07/2007 Item size : 427884 bytes

Abstract Objective: A poorly characterized phagocyte-type NADPH oxidase, which is reportedly NADH- rather than NADPH-dependent, is a major source of endothelial reactive oxygen species (ROS) ...

Cardiovascular Research, Original Article, Jian-Mei Li, Ajay M. Shah

Date : 01/12/2001 Item size : 270633 bytes

Nitric oxide (NO) influences many aspects of cardiac function including excitationcontraction coupling, myofilament function, oxygen consumption, substrate metabolism, and cell growth and survival ...

Cardiovascular Research, Editorial, Ajay M. Shah

Date : 01/06/2005 Item size : 156913 bytes

Abstract Markers of increased oxidative stress are known to be elevated following acute myocardial infarction and in the context of chronic left ventricular hypertrophy or heart failure, and their ...

Cardiovascular Research, Review, Colin E. Murdoch, Min Zhang, Alison C. Cave, Ajay M. Shah

Date : 15/07/2006

Both PF and cultured PMC superfusate induced a potent, rapidly reversible decrease in the shortening of isolated rat cardiac myocytes. Preliminary results show that the instillation of vasoactive ...

Cardiovascular Research, Original Article, Alexandre Mebazaa, Randall C. Wetzel, Jeffrey M. Dodd-o, Eileen M. Redmond, Ajay M. Shah, Kaori Maeda, Geneviève Maistre, Edward G. Lakatta, James L. ...

Date : 01/11/1998

Abstract Objectives: The production of reactive oxygen species (e.g., superoxide) by endothelial cells is relevant to tissue injury during ischemia-reperfusion, and may also play a role in ...

Cardiovascular Research, Original Article, Ulvi Bayraktutan, Nick Draper, Derek Lang, Ajay M. Shah

Date : 01/04/1998