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Abstract It is well recognized that insulin resistance found in patients with type 2 diabetes and obesity is a major risk factor for cardiovascular disease. Since its discovery in the 1920s, insulin ...

Cardiovascular Research, Yu, Qiujun, Gao, Feng, Ma, Xin L.

Date : 15/02/2011

When the Nobel prize for physiology and medicine was awarded for the discovery of the first peptide growth factors to Rita Levi-Montalcini and Stanley Cohen in 1986, Russel Ross in Seattle was among ...

Cardiovascular Research, Post, Mark, Waltenberger, Johannes

Date : 15/02/2005

Abstract Objective: Vascular endothelial growth factor (VEGF) induces the release of nitric oxide (NO) from endothelial cells. Methods: To further investigate this interaction, we examined the ...

Cardiovascular Research, Jozkowicz, Alicja, Cooke, John P, Guevara, Ibeth, Huk, Ihor, Funovics, Philip, Pachinger, Otmar, Weidinger, Franz, Dulak, Jozef

Date : 01/09/2001

Abstract Aims The chemokine receptor CXCR4 modulates endothelial progenitor cell migration, homing, and differentiation, and plays a key role in cardiovascular regeneration. In a mouse model of ...

European Heart Journal, Cencioni, Chiara, Melchionna, Roberta, Straino, Stefania, Romani, Marta, Cappuzzello, Claudia, Annese, Valentina, Wu, Joseph C., Pompilio, Giulio, Santoni, Angela, Gaetano, ...

Date : 07/07/2013 Item size : 355471 bytes

Methods and results The atherosclerotic plaque model was established in New Zealand rabbits by balloon injury of abdominal arteries and a high cholesterol (1%) diet. Arginase I overexpression ...

European Heart Journal, Wang, Xu-Ping, Zhang, Wei, Liu, Xiao-Qian, Wang, Wen-Ke, Yan, Fei, Dong, Wen-Qian, Zhang, Yun, Zhang, Ming-Xiang

Date : 07/04/2014 Item size : 288600 bytes

Estrogen receptor-α gene transfer into bovine aortic endothelial cells induces eNOS gene expression and inhibits cell migration Abstract Objectives: It has been suggested that estrogen may ...

Cardiovascular Research, Tan, Enqing, Gurjar, Milind V, Sharma, Ram V, Bhalla, Ramesh C

Date : 15/08/1999 Item size : 306500 bytes

There was no increase in apoptosis detected in eNOS transduced cells after 24 or 72 h. Conclusion: eNOS gene transfer to vascular SMCs inhibits cell proliferation via upregulation of p27 and p21 ...

Cardiovascular Research, Sato, Jun’ichi, Nair, Kamala, Hiddinga, Jay, Eberhardt, Norman L., Fitzpatrick, Lorraine A., Katusic, Zvonimir S., O’Brien, Timothy

Date : 01/09/2000

Abstract Aims Anti-platelet agents, such as dipyridamole, have several clinical benefits for peripheral artery disease with the speculation of angiogenic potential that could preserve ischaemic ...

Cardiovascular Research, Venkatesh, Prasanna K., Pattillo, Christopher B., Branch, Billy, Hood, Jay, Thoma, Steven, Illum, Sandra, Pardue, Sibile, Teng, Xinjun, Patel, Rakesh P., Kevil, Christopher G.

Date : 01/03/2010 Item size : 321116 bytes

[...]increase in vessel wall thickness and hyperplasia were shown to occur following ligation of the carotid artery in NO synthase (eNOS) knockout mice suggesting NO to be a negative regulator of ...

Cardiovascular Research, Holt, Cathy M.

Date : 01/09/2000 Item size : 134395 bytes

Following arterial injury, NO has been shown to serve many vasoprotective roles, including inhibition of platelet aggregation and adherence to the site of injury, inhibition of leukocyte adherence, ...

Cardiovascular Research, Kibbe, Melina, Billiar, Timothy, Tzeng, Edith

Date : 15/08/1999 Item size : 316572 bytes