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Abstract The ability of the endothelium to produce nitric oxide, which induces generation of cyclic guanosine monophosphate (cGMP) that activates cGMP-dependent protein kinase (PKG-I), in vascular ...

Cardiovascular Research, TOPICAL REVIEW, Hassan Sellak, Chung-sik Choi, Nupur B. Dey, Thomas M. Lincoln

Date : 01/02/2013 Item size : 502834 bytes

METHODS--Continuous inhalation of NO, initially at 15 ppm. [...]daily attempts at complete weaning or at reducing NO to the lowest effective dose. RESULTS--In 6 of the 7 children NO inhalation ...

British Heart Journal, Research Article, M. Beghetti, W. Habre, B. Friedli, M. Berner

Date : 01/01/1995

Phosphodiesterase 5 inhibition with sildenafil reverses exercise oscillatory breathing in chronic heart failure: a long‐term cardiopulmonary exercise testing placebo‐controlled study Tel/fax: ...

European Journal of Heart Failure, Guazzi, Marco, Vicenzi, Marco, Arena, Ross

Date : 01/01/2012 Item size : 171188 bytes

Tel: +1 507 284 4442, Fax: +1 507 266 0228, Email: Search for more papers by this author Abstract Heart failure with preserved ejection fraction (HFpEF) is a common but ...

European Journal of Heart Failure, Boilson, Barry A., Schirger, John A., Borlaug, Barry A.

Date : 01/01/2010 Item size : 94472 bytes

Introduction Pulmonary arterial hypertension (PAH) is a multifactorial and progressive disease, which is characterized by a sustained increase in pulmonary vascular resistance (PVR) and ultimately ...

Cardiovascular Research, Integrative physiology and pathophysiology, You-Fei Fan, Rui Zhang, Xin Jiang, Li Wen, Dan-Chen Wu, Dong Liu, Ping Yuan, Yu-Lin Wang, Zhi-Cheng Jing

Date : 01/08/2013 Item size : 332654 bytes

Abstract Almost one mountain trekker or climber out of two develops several symptoms of high altitude illness after a rapid ascent (>300 m/day) to an altitude above 4000 m. Individual ...

Cardiovascular Research, Review in Review Focus Series on Hypoxia and the Pulmonary Circulation, Marco Maggiorini

Date : 01/10/2006 Item size : 530814 bytes

The regulation of NO biosynthesis via intracellular metabolism of l-citrulline is poorly understood and may represent a novel target for therapeutic intervention for conditions associated with NO ...

Cardiovascular Research, Original Article, Candice D. Fike, Marta Sidoryk-Wegrzynowicz, Michael Aschner, Marshall Summar, Lawrence S. Prince, Gary Cunningham, Mark Kaplowitz, Yongmei Zhang, Judy L. ...

Date : 01/08/2012 Item size : 314185 bytes

Abstract Aims Members of the growth factor family of neurotrophins [NTs; e.g. brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT3)] and their high-affinity receptors (tropomyosin-related ...

Cardiovascular Research, Original Article, Lucas W. Meuchel, Michael A. Thompson, Steven D. Cassivi, Christina M. Pabelick, Y.S. Prakash

Date : 01/09/2011

Abstract Aims Uncoupled endothelial nitric oxide synthase (eNOS) is a major contributor to vascular reactive oxygen species generation in ischaemia/reperfusion (I/R) injury. Methods and results Pigs ...

Cardiovascular Research, Original Article, Seth Hallström, Maximilian Franz, Harald Gasser, Martin Vodrazka, Severin Semsroth, Udo M. Losert, Markus Haisjackl, Bruno K. Podesser, Tadeusz Malinski

Date : 01/02/2008

Introduction Pulmonary arterial hypertension (PAH) is a disease characterized by progressive narrowing of the small pulmonary arteries and arterioles due to abnormal cellular proliferation, fibrosis, ...

Cardiovascular Research, Original Article, Jason M. Aliotta, Mandy Pereira, Ashley Amaral, Arina Sorokina, Zenas Igbinoba, Alexander Hasslinger, Rabih El-Bizri, Sharon I. Rounds, Peter J. ...

Date : 01/12/2013