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Ehjcardiovascrec

The mechanisms proposed to contribute include oxygen free radical formation, calcium overload, neutrophil-mediated myocardial and endothelial injury, progressive decline in microvascular flow to the ...

Cardiovascular Research, Review, Qing-Dong Wang, John Pernow, Per-Ove Sjöquist, Lars Rydén

Date : 01/07/2002 Item size : 599139 bytes
Ehjcardiovascrec

Preconditioning, a series of transient intervals of ischaemia and reperfusion applied before the lethal index ischaemic event, sets in motion molecular and cellular mechanisms that increase ...

Cardiovascular Research, Review, Asger Granfeldt, David J. Lefer, Jakob Vinten-Johansen

Date : 15/07/2009 Item size : 648421 bytes
Ehjcardiovascrec

Most notably, activation of NF-κB appears to play a significant role in the pathophysiology of endothelial dysfunction, unstable angina pectoris, acute myocardial infarction and heart failure ...

Cardiovascular Research, Editorial, Christoph Thiemermann

Date : 01/07/2004 Item size : 179343 bytes
Ehjcardiovascrec

[...]the role of the mitochondrial uncoupling proteins in ischaemia tolerance is discussed. Mitochondria are essential organelles in any tissue, but when oxygen availability is limited they can ...

Cardiovascular Research, REVIEWS: FOCUS ON MITOCHONDRIA IN CARDIAC DISEASE, Susana Cadenas, Julián Aragonés, Manuel O. Landázuri

Date : 01/11/2010 Item size : 633400 bytes
Ehjcardiovascrec

Introduction Acute renal failure (ARF) caused by renal ischemia/reperfusion (I/R) is an important clinical problem. Studies have shown that early I/R injury can lead to the initiation of ...

Cardiovascular Research, Review, Ajay Kher, Kirstan K. Meldrum, Meijing Wang, Ben M. Tsai, Jeffrey M. Pitcher, Daniel R. Meldrum

Date : 01/09/2005 Item size : 503747 bytes
Ehjcardiovascrec

[...]we will elucidate the potential benefits and limitations of S1P analogues as a new class of functional HDL mimetics for cardiovascular therapy. Pleiotropic effects of high-density lipoproteins ...

Cardiovascular Research, Review, Katherine Sattler, Bodo Levkau

Date : 01/05/2009 Item size : 690723 bytes
Ehjcardiovascrec

In 2003, Zhao et al.11 first reported a 50% reduction of infarct size (relative to the area at risk) by PostC in an acute canine model of 60 min left anterior descending artery (LAD) occlusion ...

Cardiovascular Research, REVIEWS: SPOTLIGHT ON REDUCING MYOCARDIAL ISCHAEMIA/REPERFUSION INJURY, Weiwei Shi, Jakob Vinten-Johansen

Date : 01/05/2012 Item size : 559926 bytes
Ehjcardiovascrec

Reperfusion injury is expressed as endothelial and microvascular dysfunction, impaired blood flow, metabolic dysfunction, cellular necrosis, and apoptosis. Postconditioning may also inhibit ...

Cardiovascular Research, Review, Zhi-Qing Zhao, Jakob Vinten-Johansen

Date : 01/05/2006 Item size : 477372 bytes
Ehjcardiovascrec

Abstract Objective: Polymorphonuclear leukocytes (PMN), retained in the microvascular bed, can contribute to postischemic myocardial reperfusion injury. Since a beneficial effect of ACE-inhibition ...

Cardiovascular Research, Original Article, Christian Kupatt, Helmut Habazettl, Stefan Zahler, Christian Weber, Bernhard F Becker, Konrad Messmer, Eckehart Gerlach

Date : 01/12/1997
Ehjcardiovascrec

Conclusion: Our results demonstrated for the first time that l-arginine administered at different time points during ischemia/reperfusion exerted different effects on post-ischemic myocardial injury, ...

Cardiovascular Research, Original Article, Feng Liang, Erhe Gao, Ling Tao, Huirong Liu, Yan Qu, Theodore A Christopher, Bernard L Lopez, Xin L Ma

Date : 01/06/2004