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Introduction Atrial fibrillation (AF) is the most common cardiac arrhythmia and its prevalence will continue to increase over the next decades due to ageing of the population.1 Over the last years ...

Europace, BASIC SCIENCE, Ilse Lenaerts, Ronald B. Driesen, Nerea Hermida Blanco, Patricia Holemans, Hein Heidbüchel, Stefan Janssens, Jean-Luc Balligand, Karin R. Sipido, Rik Willems

Date : 01/05/2013 Item size : 244478 bytes

Abstract Objective: A poorly characterized phagocyte-type NADPH oxidase, which is reportedly NADH- rather than NADPH-dependent, is a major source of endothelial reactive oxygen species (ROS) ...

Cardiovascular Research, Original Article, Jian-Mei Li, Ajay M. Shah

Date : 01/12/2001 Item size : 270633 bytes

Abstract Objective: Endothelial NADPH oxidase is a major source of superoxide in blood vessels and is implicated in the oxidative stress accompanying vascular diseases, including ...

Cardiovascular Research, Original Article, Stavros Selemidis, Gregory J. Dusting, Hitesh Peshavariya, Barbara K. Kemp-Harper, Grant R. Drummond

Date : 15/07/2007 Item size : 256835 bytes

HS Jones1,2, A Gordon1,2, SG Magwenzi2, K Naseem2, SL Atkin1,3, FL Courts1,2,4 1HONEI, Hull-York Medical School, University of Hull, Hull, UK 2Centre for Cardiovascular and Metabolic Research, ...

Heart, BSCR Autumn Meeting 2014 Abstracts, HS Jones, A Gordon, SG Magwenzi, K Naseem, SL Atkin, FL Courts

Date : 01/12/2014

Superoxide anions are usually required for the generation of H2O2 and OH The generation of free radicals is a normal physiological phenomenon, which is controlled by naturally occurring scavengers ...

Cardiovascular Research, Editorial, Ghassan Bkaily, Pedro D’orléans-Juste

Date : 01/06/1999

Abstract Objective: Although studies in vitro have implicated oxygen-derived free radicals as possible mediators of inflammatory cytokine-induced cell injury, the role of the radicals in the ...

Cardiovascular Research, Original Article, Xiao-Shu Cheng, Hiroaki Shimokawa, Hidetoshi Momii, Jun-ichi Oyama, Naoto Fukuyama, Kensuke Egashira, Hiroe Nakazawa, Akira Takeshita

Date : 01/06/1999

Abstract Objective: Expression of adhesion molecules on endothelial cells and subsequent monocyte adhesion are initial events in the development of atherosclerosis. The effect of APE1/ref-1 ...

Cardiovascular Research, Original Article, Cuk Seong Kim, Sook Jin Son, Eun Kyung Kim, Seon Nyo Kim, Dae Goon Yoo, Hyo Shin Kim, Sung Woo Ryoo, Sang Do Lee, Kaikobad Irani, Byeong Hwa Jeon

Date : 01/02/2006

Abstract Objectives Recent studies have demonstrated that perivascular adipose tissue (PVAT) releases vascular relaxation factor(s). Conclusion These results show that PVAT enhances the arterial ...

Cardiovascular Research, Original Article, Yu-Jing Gao, Kumiko Takemori, Li-Ying Su, Wen-Sheng An, Chao Lu, Arya M. Sharma, Robert M.K.W. Lee

Date : 15/07/2006

Abstract The normal endothelium is characterised by the production of a number of molecules which affect the contractile state of adjacent myocytes and the behavior of formed elements within the ...

Cardiovascular Research, Review, Anthony M Dart, Jaye P.F Chin-Dusting

Date : 01/08/1999

Interactions between NO and reactive oxygen species: pathophysiological importance in atherosclerosis, hypertension, diabetes and heart failure Similar observations have been made in patients with ...

Cardiovascular Research, Review, Georg Kojda, David Harrison

Date : 15/08/1999