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Future research for validation and improvement of current clinical electrophysiology mapping technologies will be crucial for developing mechanistic-based selection and application of the best ...

Cardiovascular Research, INVITED SPOTLIGHT REVIEWS, María S. Guillem, Andreu M. Climent, Miguel Rodrigo, Francisco Fernández-Avilés, Felipe Atienza, Omer Berenfeld

Date : 01/04/2016 Item size : 531353 bytes

Introduction Metabolic syndrome with visceral fat accumulation is a major risk factor for atherosclerotic cardiovascular disease.1 Adipose tissue produces a number of adipocytokines, such as leptin ...

Cardiovascular Research, Original Article, Kaho Watanabe, Rena Watanabe, Hanae Konii, Remina Shirai, Kengo Sato, Taka-aki Matsuyama, Hatsue Ishibashi-Ueda, Shinji Koba, Youichi Kobayashi, Tsutomu ...

Date : 01/05/2016 Item size : 368317 bytes

Introduction Proprotein convertase subtilisin/kexin type 9 (PCSK9) increases plasma low-density lipoprotein (LDL) cholesterol (LDL-C) by acting as a ligand for hepatic LDL receptors (LDLR), targeting ...

Cardiovascular Research, Original Article, Hagai Tavori, Ilaria Giunzioni, Irene M. Predazzi, Deanna Plubell, Anna Shivinsky, Joshua Miles, Rachel M. Devay, Hong Liang, Shirya Rashid, MacRae F. ...

Date : 15/05/2016 Item size : 404061 bytes

[...]research in avian models69 partially argued against this model, demonstrating that: (i) prospective CA endothelial cells do not bud from the aortic root, but instead grow into the aortic wall ...

Cardiovascular Research, Review, José María Pérez-Pomares, José Luis de la Pompa, Diego Franco, Deborah Henderson, Siew Yen Ho, Lucile Houyel, Robert G. Kelly, David Sedmera, Mary ...

Date : 01/02/2016 Item size : 479037 bytes

Migration of monocytes into tissue Monocytes play a pivotal role in tissue homeostasis, protective immunity, and both promotion and resolution of inflammation.1,2 They and their offspring, ...

Cardiovascular Research, INVITED SPOTLIGHT REVIEWS, Teresa Gerhardt, Klaus Ley

Date : 01/08/2015 Item size : 622859 bytes

Abstract Leucocyte transendothelial migration (TEM) involves a co-operative series of interactions between surface molecules on the leucocyte and cognate counter-ligands on the endothelial ...

Cardiovascular Research, INVITED SPOTLIGHT REVIEWS, William A. Muller

Date : 01/08/2015 Item size : 600823 bytes

Endothelial dysfunction is an important early feature of vessel injury and promotes vasoconstriction leading to hypertension.1 Abnormal remodelling of the vessel wall is common in atherosclerosis, ...

Cardiovascular Research, TOPICAL REVIEWS, Jun Yang, Xiaohui Li, Nicholas W. Morrell

Date : 01/12/2014 Item size : 511895 bytes

[...]cardiac models have moved on significantly,3 and they are now among the best-developed theoretical representations of any organ,4 distilling years of iteration between experiment and theory.5 ...

Cardiovascular Research, TOPICAL REVIEWS: FOCUS ON CARDIOVASCULAR SYSTEMS BIOLOGY, T. Alexander Quinn, Peter Kohl

Date : 15/03/2013 Item size : 582816 bytes

Native HDL prevents platelet hyperreactivity by limiting intraplatelet cholesterol overload, as well as by modulating platelet signalling pathways after binding platelet HDL receptors such as ...

Cardiovascular Research, TOPICAL REVIEWS: SPOTLIGHT ON HDL BIOLOGY: NEW INSIGHTS IN METABOLISM, FUNCTION, AND TRANSLATION, Marco van der Stoep, Suzanne J.A. Korporaal, Miranda Van Eck

Date : 01/08/2014 Item size : 575836 bytes

A seminal early paper showed that leucotriene B molecules released from activated neutrophils trigger activation and chemokinetic migration of other neutrophils.113 The role of neutrophil-derived ...

Cardiovascular Research, INVITED SPOTLIGHT REVIEWS, Attila Mócsai, Barbara Walzog, Clifford A. Lowell

Date : 01/08/2015 Item size : 616032 bytes