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The main purpose of these studies was the differentiation of cardiac precursor cells into specialized, differentiated cell types, as well as the development of functional properties such as Ca2+ ...

Cardiovascular Research, Review, J Hescheler, B.K Fleischmann, S Lentini, V.A Maltsev, J Rohwedel, A.M Wobus, K Addicks

Date : 01/11/1997 Item size : 528145 bytes

A vicious cycle of inflammation and further oxidative stress results in increased endothelial permeability to lipoproteins and monocytes, and ultimately to atherosclerotic plaque development.1 ...

Cardiovascular Research, Vascular biology, Hayley Mylroie, Odile Dumont, Andrea Bauer, Clare C. Thornton, John Mackey, Damien Calay, Shahir S. Hamdulay, Joan R. Choo, Joseph J. Boyle, Allen M. ...

Date : 01/06/2015 Item size : 397507 bytes

Introduction Atherosclerosis is a multifactorial disease that is characterized by chronic inflammation of the arterial wall.1 Both innate and adaptive immune responses play vital roles in the process ...

Cardiovascular Research, Vascular biology, Wencai Zhang, Tingting Tang, Daan Nie, Shuang Wen, Chenping Jia, Zhengfeng Zhu, Ni Xia, Shaofang Nie, Sufeng Zhou, Jiao Jiao, Wenyong Dong, Bingjie Lv, ...

Date : 01/06/2015 Item size : 403832 bytes

According to the well-accepted endosymbiotic theory, mitochondria are the direct descendants of an α-proteobacteria endosymbiont that became established in a host cell. The double-strand circular ...

Cardiovascular Research, Review, Renée Ventura-Clapier, Anne Garnier, Vladimir Veksler

Date : 15/07/2008 Item size : 469948 bytes

Abstract Objective: To establish if the mouse with trisomy 16 is a suitable animal model with which to elucidate the development of a common atrioventricular junction. The difficulty in proving this ...

Cardiovascular Research, Review, Robert H Anderson, Sandra Webb, Nigel A Brown

Date : 01/07/1998 Item size : 253979 bytes

Introduction Efficiency of excitationcontraction in the adult ventricular myocyte is enhanced by the structural features of this highly organised cell, with its scalloped surface formed by periodic ...

Cardiovascular Research, Original Article, Julia Gorelik, Lin Q. Yang, Yanjun Zhang, Max Lab, Yuri Korchev, Sian E. Harding

Date : 01/12/2006 Item size : 223827 bytes

Vertebrate heart development can be subdivided into different phases, e.g. specification of myo- and endocardial progenitor cells during the establishment of heart-forming fields within the anterior ...

Cardiovascular Research, Review, Thomas Brade, Jörg Männer, Michael Kühl

Date : 01/11/2006 Item size : 488827 bytes

Methods and results We used several types of cultured mouse, rat, and bovine cells from the cardiovascular system, and evaluated mitochondrial morphology, reactive oxygen species (ROS) levels, and ...

Cardiovascular Research, Original Article, Tianzheng Yu, Shey-Shing Sheu, James L. Robotham, Yisang Yoon

Date : 15/07/2008 Item size : 328023 bytes

For several reasons, it is not possible to make a precise judgement on the absolute value of the model in terms of its ability to accurately predict the effectiveness of drugs in the prevention of ...

Cardiovascular Research, Review, Michael J Curtis

Date : 01/07/1998 Item size : 525714 bytes

Abstract The development of efficient transgenic technologies in mice has allowed the study of the consequences of genetic alterations on cardiovascular (patho)physiology, although the development of ...

Cardiovascular Research, Review, Peter Carmeliet, Lieve Moons, Désiré Collen

Date : 01/07/1998 Item size : 965541 bytes