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Ehjcardiovascrec

Catheter ablation of atrial fibrillation and outcomes in heart failure patients: seeking the treasure in the CASTLE There are reasons to believe that maintenance of normal sinus rhythm (SR) might ...

Cardiovascular Research, Nattel, Stanley

Date : 01/06/2018
Ehjcardiovascrec

Patients with HFpEF have cardiac and extra-cardiac manifestations, including LV diastolic dysfunction, abnormal heart rate and rhythm, microvascular dysfunction, increased aortic stiffness, and ...

Cardiovascular Research, O’Gallagher, Kevin, Shah, Ajay M

Date : 01/06/2018 Item size : 139956 bytes
Ehjcardiovascrec

Introduction More than 50% of patients with heart failure present with heart failure with preserved ejection fraction (HFpEF), characterized by diastolic dysfunction.1 Hospitalized patients with ...

Cardiovascular Research, Sorop, Oana, Heinonen, Ilkka, van Kranenburg, Matthijs, van de Wouw, Jens, de Beer, Vincent J, Nguyen, Isabel T N, Octavia, Yanti, van Duin, Richard W B, Stam, Kelly, van ...

Date : 01/06/2018
Ehjcardiovascrec

[...]we introduce the concept of integrating stem cell models with computational modelling to create a novel pipeline for patient-specific drug discovery and development. 1. Importantly, some ion ...

Cardiovascular Research, Barichello, Scott, Roberts, Jason D, Backx, Peter, Boyle, Patrick M, Laksman, Zachary

Date : 01/06/2018
Ehjcardiovascrec

Dietary fat is a key determinant in balancing mitochondrial dynamics in heart failure: a novel mechanism underlying the obesity paradox Shifting from fatty acid to glucose oxidation The main feature ...

Cardiovascular Research, De Rosa, Matteo, Gambardella, Jessica, Shu, Jun, Santulli, Gaetano

Date : 01/06/2018 Item size : 158966 bytes
Ehjcardiovascrec

The classical MR ligand is aldosterone that after binding in renal epithelial cells induces the expression of proteins important for water and sodium retention. Since this results in a rise of blood ...

Cardiovascular Research, van der Heijden, Charlotte D C C, Deinum, Jaap, Joosten, Leo A B, Netea, Mihai G, Riksen, Niels P

Date : 01/06/2018
Ehjcardiovascrec

Abstract Aims Angiotensin II (Ang II) causes vascular inflammation, leading to vascular endothelial cell dysfunction, and is associated with the development of cardiovascular ...

Cardiovascular Research, Yang, Di, Xiao, ChenXi, Long, Fen, Su, ZhengHua, Jia, WanWan, Qin, Ming, Huang, MengWei, Wu, WeiJun, Suguro, Rinkiko, Liu, XinHua, Zhu, YiZhun

Date : 01/06/2018
Ehjcardiovascrec

Congenital heart disease and the role of the SlitRobo signalling pathway Congenital heart disease affects 1% of all live births1 and includes a wide range of conditions such as ventricular septal ...

Cardiovascular Research, Zhao, Juanjuan, Mommersteeg, Mathilda T M

Date : 01/05/2018 Item size : 462816 bytes
Ehjcardiovascrec

Just over a decade ago, it was reported for the first time that microRNAs (miRs) play central roles in the control of cardiomyocyte (CM) proliferation and differentiation.1 Especially fascinating has ...

Cardiovascular Research, Alfar, Ezzaldin Ahmed, El-Armouche, Ali, Guan, Kaomei

Date : 01/05/2018
Ehjcardiovascrec

Abstract Aims Mitochondrial creatine kinase (MtCK) couples ATP production via oxidative phosphorylation to phosphocreatine in the cytosol, which acts as a mobile energy store available for ...

Cardiovascular Research, Whittington, Hannah J, Ostrowski, Philip J, McAndrew, Debra J, Cao, Fang, Shaw, Andrew, Eykyn, Thomas R, Lake, Hannah A, Tyler, Jack, Schneider, Jurgen E, Neubauer, Stefan, ...

Date : 01/05/2018 Item size : 375684 bytes