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Ehjcardiovascrec

Methods: The effect of several concentrations of KB-R7943 added at reperfusion was studied in Fura-2 loaded quiescent cardiomyocytes submitted to 40 min of simulated ischemia (NaCN 2 mM, pH 6.4), and ...

Cardiovascular Research, Original Article, Javier Inserte, David Garcia-Dorado, Marisol Ruiz-Meana, Ferran Padilla, José A Barrabés, Pilar Pina, Luis Agulló, Hans Michael Piper, Jordi ...

Date : 01/09/2002 Item size : 271773 bytes
Ehjcardiovascrec

An analysis of the underlying causes identifies improvements in quality of care and treatment as a major cause, accounting from 50 up to 75% of the success depending on the study samples, the ...

Cardiovascular Research, VIEWPOINT EDITORIAL, Karin R. Sipido, Alain Tedgui, Steen D. Kristensen, Gerard Pasterkamp, Heribert Schunkert, Martin Wehling, Philippe G. Steg, Wolfgang Eisert, Frank ...

Date : 01/08/2009 Item size : 477459 bytes
Ehjcardiovascrec

Methods Intracellular Na+ concentration ([Na+]i) measured using 23Na-magnetic resonance spectroscopy, Na+/K+-ATPase activity, detachment of Na+/K+-ATPase α subunits from the membrane cytoskeleton, ...

Cardiovascular Research, Original Article, Javier Inserte, David Garcia-Dorado, Victor Hernando, Ignasi Barba, Jordi Soler-Soler

Date : 01/05/2006 Item size : 287033 bytes
Ehjcardiovascrec

Introduction Since the protection afforded by brief episodes of ischemia against cell death induced by subsequent prolonged ischemia and reperfusion was originally described in 1986 [1], an enormous ...

Cardiovascular Research, Review, David Garcia-Dorado, Antonio Rodriguez-Sinovas, Marisol Ruiz-Meana, Javier Inserte, Luis Agulló, Alberto Cabestrero

Date : 01/05/2006 Item size : 490461 bytes
Ehjcardiovascrec

The potential for clinical application to benefit patients with a variety of pathological conditions has led to an expansion in our knowledge concerning the pathophysiology of ischemia-reperfusion ...

Cardiovascular Research, Review, Derek M Yellon, Gary F Baxter, David Garcia-Dorado, Gerd Heusch, Mark S Sumeray

Date : 01/01/1998 Item size : 550548 bytes
Ehjcardiovascrec

Abstract Aims It has been shown that sarcoplasmic reticulum calcium ATPase (SERCA) plays a critical role in reperfusion injury. [...]ischaemic post-conditioning (PoCo) results in protein kinase G ...

Cardiovascular Research, Cardiac biology and remodelling, Javier Inserte, Víctor Hernando, Marisol Ruiz-Meana, Marcos Poncelas-Nozal, Celia Fernández, Luis Agulló, Carmem Sartorio, Úrsula ...

Date : 01/09/2014 Item size : 366352 bytes
Ehjcardiovascrec

Abstract Objective: Connexin 43 (Cx43) is involved in infarct size reduction by ischemic preconditioning (IP); the underlying mechanism of protection, however, is unknown. Since mitochondria have ...

Cardiovascular Research, Original Article, Kerstin Boengler, Giuliano Dodoni, Antonio Rodriguez-Sinovas, Alberto Cabestrero, Marisol Ruiz-Meana, Petra Gres, Ina Konietzka, Carmen Lopez-Iglesias, ...

Date : 01/08/2005 Item size : 293759 bytes
Ehjcardiovascrec

[...]SR and mitochondria interact physiologically to control cellular Ca2+ homeostasis. Alterations in the function of the SR are now known to be of primary importance for the development of ...

Cardiovascular Research, Editorial, David Garcia-Dorado, Hans Michael Piper, David A. Eisner

Date : 15/01/2008 Item size : 191287 bytes
Ehjcardiovascrec

The greatest progress has been made in methods to mechanically or chemically re-open acutely occluded coronary arteries and in increasingly better logistics of pre-hospital treatment and patient ...

Cardiovascular Research, EDITORIAL: SPOTLIGHT ON REDUCING MYOCARDIAL ISCHAEMIA/REPERFUSION INJURY, Hans Michael Piper, David Garcia-Dorado

Date : 01/05/2012 Item size : 193006 bytes
Ehjcardiovascrec

The original description Twenty-five years is a long time in biomedical research, and most of today's cardiovascular scientists were at university or high school when ischaemic preconditioning was ...

Cardiovascular Research, VIEWPOINT EDITORIAL, David Garcia-Dorado, Ignasi Barba, Javier Inserte

Date : 01/08/2011 Item size : 214564 bytes