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Ehjcardiovascrec

Methods: The effect of several concentrations of KB-R7943 added at reperfusion was studied in Fura-2 loaded quiescent cardiomyocytes submitted to 40 min of simulated ischemia (NaCN 2 mM, pH 6.4), and ...

Cardiovascular Research, Original Article, Javier Inserte, David Garcia-Dorado, Marisol Ruiz-Meana, Ferran Padilla, José A Barrabés, Pilar Pina, Luis Agulló, Hans Michael Piper, Jordi ...

Date : 01/09/2002 Item size : 271773 bytes
Ehjcardiovascrec

Introduction Since the protection afforded by brief episodes of ischemia against cell death induced by subsequent prolonged ischemia and reperfusion was originally described in 1986 [1], an enormous ...

Cardiovascular Research, Review, David Garcia-Dorado, Antonio Rodriguez-Sinovas, Marisol Ruiz-Meana, Javier Inserte, Luis Agulló, Alberto Cabestrero

Date : 01/05/2006 Item size : 490461 bytes
Ehjcardiovascrec

Abstract Aims It has been shown that sarcoplasmic reticulum calcium ATPase (SERCA) plays a critical role in reperfusion injury. [...]ischaemic post-conditioning (PoCo) results in protein kinase G ...

Cardiovascular Research, Cardiac biology and remodelling, Javier Inserte, Víctor Hernando, Marisol Ruiz-Meana, Marcos Poncelas-Nozal, Celia Fernández, Luis Agulló, Carmem Sartorio, Úrsula ...

Date : 01/09/2014 Item size : 366352 bytes
Ehjcardiovascrec

Abstract Objective: Connexin 43 (Cx43) is involved in infarct size reduction by ischemic preconditioning (IP); the underlying mechanism of protection, however, is unknown. Since mitochondria have ...

Cardiovascular Research, Original Article, Kerstin Boengler, Giuliano Dodoni, Antonio Rodriguez-Sinovas, Alberto Cabestrero, Marisol Ruiz-Meana, Petra Gres, Ina Konietzka, Carmen Lopez-Iglesias, ...

Date : 01/08/2005 Item size : 293759 bytes
Ehjcardiovascrec

Methods and results Pigs were submitted to 40 min of coronary occlusion followed by reperfusion, and received (i) no treatment, (ii) one of the following treatments: RIC (5 min ischemia/5 min ...

Cardiovascular Research, Original Article, Juan José Alburquerque-Béjar, Ignasi Barba, Javier Inserte, Elisabet Miró-Casas, Marisol Ruiz-Meana, Marcos Poncelas, Úrsula Vilardosa, Laura ...

Date : 15/07/2015 Item size : 344631 bytes
Ehjcardiovascrec

Remarkably, as the ΔΨm dissipates, i.e. under hypoxic conditions or when H+ influx follows an alternative route not coupled to energy production, mitochondria can act as ATP consumers by ...

Cardiovascular Research, REVIEWS: FOCUS ON MITOCHONDRIA IN CARDIAC DISEASE, Marisol Ruiz-Meana, Celia Fernandez-Sanz, David Garcia-Dorado

Date : 01/10/2010 Item size : 637391 bytes
Ehjcardiovascrec

In myocardium, gap junction communication is altered during ischemia, which contributes to the development of arrhythmias, but still allows synchronization of the onset of rigor contracture in the ...

Cardiovascular Research, Review, David Garcia-Dorado, Marisol Ruiz-Meana, Ferran Padilla, Antonio Rodriguez-Sinovas, Maribel Mirabet

Date : 15/08/2002 Item size : 519924 bytes
Ehjcardiovascrec

Conclusion: These results indicate that inhibition of Na+H+ exchange during ischemia is necessary to limit myocardial necrosis secondary to transient coronary occlusion, and that this action could be ...

Cardiovascular Research, Original Article, David Garcia-Dorado, Miguel A González, José A Barrabés, Marisol Ruiz-Meana, Julia Solares, Rosa-Maria Lidon, José Blanco, Yolanda Puigfel, ...

Date : 01/07/1997
Ehjcardiovascrec

Methods and results The effect of acidic perfusion on reperfusion injury was studied in isolated rat hearts submitted to 40 min of ischaemia and 30 min of reperfusion, and its effect on the ...

Cardiovascular Research, ORIGINALS, Javier Inserte, Ignasi Barba, Víctor Hernando, Arancha Abellán, Marisol Ruiz-Meana, Antonio Rodríguez-Sinovas, David Garcia-Dorado

Date : 01/03/2008
Ehjcardiovascrec

[...]the so-called Ca2+ paradox (hypercontracture and death of cardiomyocytes occurring upon restoration of Ca2+ after a Ca2+-free perfusion period) was meant to be a first cellular model of ...

Cardiovascular Research, REVIEWS: SPOTLIGHT ON REDUCING MYOCARDIAL ISCHAEMIA/REPERFUSION INJURY, David Garcia-Dorado, Marisol Ruiz-Meana, Javier Inserte, Antonio Rodriguez-Sinovas, Hans Michael Piper

Date : 01/05/2012