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[...]SR and mitochondria interact physiologically to control cellular Ca2+ homeostasis. Alterations in the function of the SR are now known to be of primary importance for the development of ...

Cardiovascular Research, Editorial, David Garcia-Dorado, Hans Michael Piper, David A. Eisner

Date : 15/01/2008 Item size : 191287 bytes

Protecting the heart from ischaemia- and reperfusion-induced injury represents the greatest challenge of cardiology, since myocardial infarction is the major cause of mortality in industrialized ...

Cardiovascular Research, Editorial, Hans Michael Piper, David Garcia-Dorado

Date : 15/07/2009 Item size : 141983 bytes

Remarkably, as the ΔΨm dissipates, i.e. under hypoxic conditions or when H+ influx follows an alternative route not coupled to energy production, mitochondria can act as ATP consumers by ...

Cardiovascular Research, REVIEWS: FOCUS ON MITOCHONDRIA IN CARDIAC DISEASE, Marisol Ruiz-Meana, Celia Fernandez-Sanz, David Garcia-Dorado

Date : 01/10/2010 Item size : 637391 bytes

Introduction In patients with ST-segment elevation acute myocardial infarction (AMI), the main therapeutic goal is to restore coronary flow as soon as possible by means of percutaneous intervention ...

Cardiovascular Research, Review, Javier Inserte, José A. Barrabés, Víctor Hernando, David Garcia-Dorado

Date : 15/07/2009 Item size : 489326 bytes