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Protecting the heart from ischaemia- and reperfusion-induced injury represents the greatest challenge of cardiology, since myocardial infarction is the major cause of mortality in industrialized ...

Cardiovascular Research, Editorial, Hans Michael Piper, David Garcia-Dorado

Date : 15/07/2009 Item size : 141983 bytes

Introduction In patients with ST-segment elevation acute myocardial infarction (AMI), the main therapeutic goal is to restore coronary flow as soon as possible by means of percutaneous intervention ...

Cardiovascular Research, Review, Javier Inserte, José A. Barrabés, Víctor Hernando, David Garcia-Dorado

Date : 15/07/2009 Item size : 489326 bytes

The mechanisms of protection by postconditioning include: formation and release of several autacoids and cytokines; maintained acidosis during early reperfusion; activation of protein kinases; ...

Cardiovascular Research, Review, Michel Ovize, Gary F. Baxter, Fabio Di Lisa, Péter Ferdinandy, David Garcia-Dorado, Derek J. Hausenloy, Gerd Heusch, Jakob Vinten-Johansen, Derek M. Yellon, Rainer ...

Date : 01/08/2010