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Ehjcardiovascrec

Methods: The effect of several concentrations of KB-R7943 added at reperfusion was studied in Fura-2 loaded quiescent cardiomyocytes submitted to 40 min of simulated ischemia (NaCN 2 mM, pH 6.4), and ...

Cardiovascular Research, Original Article, Javier Inserte, David Garcia-Dorado, Marisol Ruiz-Meana, Ferran Padilla, José A Barrabés, Pilar Pina, Luis Agulló, Hans Michael Piper, Jordi ...

Date : 01/09/2002 Item size : 271773 bytes
Ehjcardiovascrec

Introduction Since the protection afforded by brief episodes of ischemia against cell death induced by subsequent prolonged ischemia and reperfusion was originally described in 1986 [1], an enormous ...

Cardiovascular Research, Review, David Garcia-Dorado, Antonio Rodriguez-Sinovas, Marisol Ruiz-Meana, Javier Inserte, Luis Agulló, Alberto Cabestrero

Date : 01/05/2006 Item size : 490461 bytes
Ehjcardiovascrec

Despite its overall beneficial effect, experimental myocardial reperfusion was associated with prominent arrhythmias, enzyme release, and other adverse phenomena that were grouped under the imprecise ...

Cardiovascular Research, Viewpoint Editorial, David Garcia-Dorado, Hans Michael Piper

Date : 01/01/2006 Item size : 186761 bytes
Ehjcardiovascrec

Introduction In patients with ST-segment elevation acute myocardial infarction (AMI), the main therapeutic goal is to restore coronary flow as soon as possible by means of percutaneous intervention ...

Cardiovascular Research, Review, Javier Inserte, José A. Barrabés, Víctor Hernando, David Garcia-Dorado

Date : 15/07/2009 Item size : 489326 bytes
Ehjcardiovascrec

The purpose of this study was to determine whether stimulation of particulate guanylyl cyclase with the natriuretic peptide urodilatin, given at the time of reperfusion, reduces myocardial necrosis ...

Cardiovascular Research, Original Article, Javier Inserte, David Garcia-Dorado, Luis Agulló, Amaya Paniagua, Jordi Soler-Soler

Date : 14/01/2000
Ehjcardiovascrec

The mechanisms of protection by postconditioning include: formation and release of several autacoids and cytokines; maintained acidosis during early reperfusion; activation of protein kinases; ...

Cardiovascular Research, Review, Michel Ovize, Gary F. Baxter, Fabio Di Lisa, Péter Ferdinandy, David Garcia-Dorado, Derek J. Hausenloy, Gerd Heusch, Jakob Vinten-Johansen, Derek M. Yellon, Rainer ...

Date : 01/08/2010
Ehjcardiovascrec

[...]in animals, interventions against lethal reperfusion injury are usually tested in the absence of other medications, in contrast to what happens in patients with acute coronary syndrome. Recent ...

Cardiovascular Research, VIEWPOINT EDITORIAL, David Garcia-Dorado, Marisol Ruiz-Meana, Hans Michael Piper

Date : 15/07/2009
Ehjcardiovascrec

The present Spotlight Issue presents a series of review articles with the aim of providing an up-to-date overview of the state of the art in the rapidly moving field of research on endogenous ...

Cardiovascular Research, Editorial, David Garcia-Dorado, Jacob Vinten-Johansen, Hans Michael Piper

Date : 01/05/2006