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The innate immune system plays an important role in this process, mediating rapid influx of immune cells into the reperfused myocardium. Methods and results Male C57Bl/6J mice were subjected to ...

Cardiovascular Research, de Hoog, Vince C., Bovens, Sandra M., de Jager, Saskia C.A., van Middelaar, Ben J., van Duijvenvoorde, Amerik, Doevendans, Pieter A., Pasterkamp, Gerard, de Kleijn, Dominique ...

Date : 01/12/2015 Item size : 342333 bytes

Previous studies generated transgenic mice expressing D-type cyclins under the transcriptional regulation of the alpha-cardiac myosin heavy chain (MHC) promoter in an effort to promote cardiomyocyte ...

Cardiovascular Research, Hassink, Rutger J., Pasumarthi, Kishore B., Nakajima, Hidehiro, Rubart, Michael, Soonpaa, Mark H., de la Rivière, Aart Brutel, Doevendans, Pieter A., Field, Loren J.

Date : 01/04/2008 Item size : 268006 bytes

Methods and results Meta-analysis and regression of large animal studies were performed to identify sources that influenced effect size of anti-inflammatory compounds in large animal models of ...

Cardiovascular Research, van Hout, Gerardus P. J., Jansen of Lorkeers, Sanne J., Wever, Kimberly E., Sena, Emily S., Kouwenberg, Lisanne H. J. A., van Solinge, Wouter W., Macleod, Malcolm R., ...

Date : 01/02/2016 Item size : 388930 bytes

Contribution of serum response factor and myocardin to transcriptional regulation of smoothelins Conclusion Smoothelin-A expression is controlled by an intragenic promoter whose activity is, in ...

Cardiovascular Research, Rensen, Sander S.M., Niessen, Petra M.G., Long, Xiaochun, Doevendans, Pieter A., Miano, Joseph M., van Eys, Guillaume J.J.M.

Date : 01/04/2006

Various cell types have been successfully employed in the recovery of cardiac damage by reducing inflammation, activating endogenous regenerative responses, and, in some cases, directly participating ...

Cardiovascular Research, Feyen, Dries, Gaetani, Roberto, Liu, Jia, Noort, Willy, Martens, Anton, den Ouden, Krista, Doevendans, Pieter A., Sluijter, Joost P.G.

Date : 01/07/2013

Abstract The heart is an organ with a complex mixture of well-organized interactions of different cell types that facilitate proper myocardial contractility, sufficient perfusion, balanced myocardial ...

Cardiovascular Research, Sluijter, Joost P.G., Verhage, Vera, Deddens, Janine C., van den Akker, Frederieke, Doevendans, Pieter A.

Date : 01/05/2014 Item size : 469240 bytes

Programmed cell death (apoptosis) of cardiac muscle cells has been identified as an essential process in the progression to heart failure. [...]the present review summarizes the apoptotic pathways ...

Cardiovascular Research, van Empel, Vanessa P.M., Bertrand, Anne T.A., Hofstra, Leo, Crijns, Harry J., Doevendans, Pieter A., De Windt, Leon J.

Date : 01/07/2005

Abstract Aims Mononuclear cells (MNCs) from patients with hereditary haemorrhagic telangiectasia type 1 (HHT1), a genetic disorder caused by mutations in endoglin, show a reduced ability to home to ...

Cardiovascular Research, Post, Simone, Smits, Anke M., van den Broek, Alexandra J., Sluijter, Joost P.G., Hoefer, Imo E., Janssen, Ben J., Snijder, Repke J., Mager, Johannes J., Pasterkamp, Gerard, ...

Date : 01/02/2010

Cell therapy potentially includes embryonic and bone marrow-derived stem cells.1 Recently, the existence of cardiac stem cells that reside in the heart itself was demonstrated. Gaetani et al.3 ...

Cardiovascular Research, Chamuleau, Steven A.J., van Belle, Eric, Doevendans, Pieter A.

Date : 01/06/2009 Item size : 145702 bytes

[2] (pages 630639) in this issue. 1 Introduction Restenosis has been troubling patients and cardiologists, following percutaneous transluminal coronary angioplasty (PTCA), since the technique was ...

Cardiovascular Research, Doevendans, Pieter A., van Eys, Guillaume

Date : 01/06/2002 Item size : 170289 bytes