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Inhibition of the Na+/H+ exchanger attenuates the deterioration of ventricular function during pacing-induced heart failure in rabbits In sham rabbits treated with placebo (n=9) or BIIB722 (30 ...

Cardiovascular Research, Aker, Stephanie, Snabaitis, Andrew K, Konietzka, Ina, van de Sand, Anita, Böngler, Kerstin, Avkiran, Metin, Heusch, Gerd, Schulz, Rainer

Date : 01/08/2004 Item size : 315726 bytes

Methods and results In this study we verified the presence of mCx43 by a mass spectrometry-based proteomic approach in purified mitochondrial preparations from mouse myocardium and determined by ...

Cardiovascular Research, Miro-Casas, Elisabet, Ruiz-Meana, Marisol, Agullo, Esperanza, Stahlhofen, Sabine, Rodrı́guez-Sinovas, Antonio, Cabestrero, Alberto, Jorge, Inmaculada, Torre, Iratxe, ...

Date : 01/09/2009

[...]mechanisms independent of the NOS pathway have been suggested to contribute to NO synthesis during ischemia. NO initiates detrimental as well as protective mechanisms in a ...

Cardiovascular Research, Martin, Claus, Schulz, Rainer, Post, Heiner, Boengler, Kerstin, Kelm, Malte, Kleinbongard, Petra, Gres, Petra, Skyschally, Andreas, Konietzka, Ina, Heusch, Gerd

Date : 01/04/2007

Introduction The present review discusses factors affecting gating properties of connexin 43 (Cx43)-formed channels (hemichannels, gap junctions) and their alterations by single or repetitive periods ...

Cardiovascular Research, Schulz, Rainer, Heusch, Gerd

Date : 01/05/2004 Item size : 608569 bytes

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Cardiovascular Research, Heusch, Gerd

Date : 01/01/1992 Item size : 107238 bytes

During the last three decades, a wide variety of ischaemic conditioning strategies and pharmacological treatments have been tested in the clinichowever, their translation from experimental to ...

Cardiovascular Research, Hausenloy, Derek J., Garcia-Dorado, David, Bøtker, Hans Erik, Davidson, Sean M., Downey, James, Engel, Felix B., Jennings, Robert, Lecour, Sandrine, Leor, Jonathan, ...

Date : 01/05/2017

Introduction Atherosclerotic plaque rupture, occurring either spontaneously or during coronary interventions, results in the release of atheromatous and/or thrombotic material into the coronary ...

Cardiovascular Research, Skyschally, Andreas, Schulz, Rainer, Gres, Petra, Konietzka, Ina, Martin, Claus, Haude, Michael, Erbel, Raimund, Heusch, Gerd

Date : 01/08/2004 Item size : 289509 bytes

Cardioprotection is a relatively vague term which more specifically refers to all interventions that reduce myocardial ischemia/reperfusion injury.1 In experimental animals, the most robust endpoint ...

Cardiovascular Research, Heusch, Gerd

Date : 01/11/2015

Because of this, there is currently no effective therapy for protecting the heart against the detrimental effects of acute IRI in patients with CHD. According to the World Health Organisation (WHO), ...

Cardiovascular Research, Hausenloy, Derek J., Bøtker, Hans Erik, Condorelli, Gianluigi, Ferdinandy, Peter, Garcia-Dorado, David, Heusch, Gerd, Lecour, Sandrine, van Laake, Linda W., Madonna, ...

Date : 01/04/2013

[...]novel therapies are still needed to protect the heart from the detrimental effects of acute ischaemiareperfusion injury, in order to improve clinical outcomes in IHD patients. [...]the aim of ...

Cardiovascular Research, Lecour, Sandrine, Bøtker, Hans E., Condorelli, Gianluigi, Davidson, Sean M., Garcia-Dorado, David, Engel, Felix B., Ferdinandy, Peter, Heusch, Gerd, Madonna, Rosalinda, ...

Date : 01/12/2014 Item size : 613656 bytes