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The genes, structure, and cell-type expression patterns of the different connexins have been recently and extensively reviewed, as well as the functional properties, molecular interactions and ...

Cardiovascular Research, Ruiz-Meana, Marisol, Rodríguez-Sinovas, Antonio, Cabestrero, Alberto, Boengler, Kerstin, Heusch, Gerd, Garcia-Dorado, David

Date : 15/01/2008 Item size : 443366 bytes

Abstract Administration of nitric oxide (NO), NO donors or drugs that enhance NO realease (statins, calcium antagonists, ACE-inhibitors, dexamethasone) prior to ischemia protects the myocardium ...

Cardiovascular Research, Schulz, Rainer, Kelm, Malte, Heusch, Gerd

Date : 15/02/2004

The pivotal importance of myocardial perfusion for the maintenance of myocardial contractile function was already recognized some 60 years ago [1], but the functional and metabolic consequences of ...

Cardiovascular Research, Duncker, Dirk J, Schulz, Rainer, Ferrari, Roberto, Garcia-Dorado, David, Guarnieri, Carlo, Heusch, Gerd, Verdouw, Pieter D

Date : 01/06/1998

[...]mechanisms independent of the NOS pathway have been suggested to contribute to NO synthesis during ischemia. NO initiates detrimental as well as protective mechanisms in a ...

Cardiovascular Research, Martin, Claus, Schulz, Rainer, Post, Heiner, Boengler, Kerstin, Kelm, Malte, Kleinbongard, Petra, Gres, Petra, Skyschally, Andreas, Konietzka, Ina, Heusch, Gerd

Date : 01/04/2007 Item size : 314405 bytes

[...]novel therapies are still needed to protect the heart from the detrimental effects of acute ischaemiareperfusion injury, in order to improve clinical outcomes in IHD patients. [...]the aim of ...

Cardiovascular Research, Lecour, Sandrine, Bøtker, Hans E., Condorelli, Gianluigi, Davidson, Sean M., Garcia-Dorado, David, Engel, Felix B., Ferdinandy, Peter, Heusch, Gerd, Madonna, Rosalinda, ...

Date : 01/12/2014

Cardioprotection is a relatively vague term which more specifically refers to all interventions that reduce myocardial ischemia/reperfusion injury.1 In experimental animals, the most robust endpoint ...

Cardiovascular Research, Heusch, Gerd

Date : 01/11/2015 Item size : 194517 bytes

During the last three decades, a wide variety of ischaemic conditioning strategies and pharmacological treatments have been tested in the clinichowever, their translation from experimental to ...

Cardiovascular Research, Hausenloy, Derek J., Garcia-Dorado, David, Bøtker, Hans Erik, Davidson, Sean M., Downey, James, Engel, Felix B., Jennings, Robert, Lecour, Sandrine, Leor, Jonathan, ...

Date : 01/05/2017 Item size : 1110835 bytes

Remote ischemic conditioning is the systemic response to brief non-lethal ischemia/reperfusion in various tissues or organs which provides protection to a number of target tissues or organs over a ...

Cardiovascular Research, Heusch, Gerd

Date : 01/01/2017 Item size : 178418 bytes

Professor Gerd Heusch is director for the Institute of Pathophysiology and scientific chief executive of the West German Heart and Vascular Center at the University of Essen Medical School. The ...

Cardiovascular Research, Heusch, Gerd

Date : 01/08/2017 Item size : 151252 bytes

Universitat Autònoma, Barcelona, Spain; Department of Cardiology, Aarhus University Hospital Skejby, DK-8200, Aarhus N, Denmark; The Hatter Cardiovascular Institute, University College London, ...

Cardiovascular Research, Hausenloy, Derek J., Garcia-Dorado, David, Erik Bøtker, Hans, Davidson, Sean M., Downey, James, Engel, Felix B., Jennings, Robert, Lecour, Sandrine, Leor, Jonathan, ...

Date : 01/09/2017 Item size : 460008 bytes