Methods and results In this study we verified the presence of mCx43 by a mass spectrometry-based proteomic approach in purified mitochondrial preparations from mouse myocardium and determined by ...
Cardiovascular Research, Miro-Casas, Elisabet, Ruiz-Meana, Marisol, Agullo, Esperanza, Stahlhofen, Sabine, RodrıÌguez-Sinovas, Antonio, Cabestrero, Alberto, Jorge, Inmaculada, Torre, Iratxe, ...
During the last three decades, a wide variety of ischaemic conditioning strategies and pharmacological treatments have been tested in the clinichowever, their translation from experimental to ...
Cardiovascular Research, Hausenloy, Derek J., Garcia-Dorado, David, Bøtker, Hans Erik, Davidson, Sean M., Downey, James, Engel, Felix B., Jennings, Robert, Lecour, Sandrine, Leor, Jonathan, ...
Because of this, there is currently no effective therapy for protecting the heart against the detrimental effects of acute IRI in patients with CHD. According to the World Health Organisation (WHO), ...
Cardiovascular Research, Hausenloy, Derek J., Bøtker, Hans Erik, Condorelli, Gianluigi, Ferdinandy, Peter, Garcia-Dorado, David, Heusch, Gerd, Lecour, Sandrine, van Laake, Linda W., Madonna, ...
[...]novel therapies are still needed to protect the heart from the detrimental effects of acute ischaemiareperfusion injury, in order to improve clinical outcomes in IHD patients. [...]the aim of ...
Cardiovascular Research, Lecour, Sandrine, Bøtker, Hans E., Condorelli, Gianluigi, Davidson, Sean M., Garcia-Dorado, David, Engel, Felix B., Ferdinandy, Peter, Heusch, Gerd, Madonna, Rosalinda, ...
The genes, structure, and cell-type expression patterns of the different connexins have been recently and extensively reviewed, as well as the functional properties, molecular interactions and ...
Cardiovascular Research, Ruiz-Meana, Marisol, RodrÃguez-Sinovas, Antonio, Cabestrero, Alberto, Boengler, Kerstin, Heusch, Gerd, Garcia-Dorado, David
The pivotal importance of myocardial perfusion for the maintenance of myocardial contractile function was already recognized some 60 years ago [1], but the functional and metabolic consequences of ...
Cardiovascular Research, Duncker, Dirk J, Schulz, Rainer, Ferrari, Roberto, Garcia-Dorado, David, Guarnieri, Carlo, Heusch, Gerd, Verdouw, Pieter D
Abstract Objective: Connexin 43 (Cx43) is involved in infarct size reduction by ischemic preconditioning (IP); the underlying mechanism of protection, however, is unknown. Since mitochondria have ...
Cardiovascular Research, Boengler, Kerstin, Dodoni, Giuliano, Rodriguez-Sinovas, Antonio, Cabestrero, Alberto, Ruiz-Meana, Marisol, Gres, Petra, Konietzka, Ina, Lopez-Iglesias, Carmen, Garcia-Dorado, ...
The potential for clinical application to benefit patients with a variety of pathological conditions has led to an expansion in our knowledge concerning the pathophysiology of ischemia-reperfusion ...
Cardiovascular Research, Yellon, Derek M, Baxter, Gary F, Garcia-Dorado, David, Heusch, Gerd, Sumeray, Mark S
The potential for clinical application to benefit patients with a variety of pathological conditions has led to an expansion in our knowledge concerning the pathophysiology of ischemia-reperfusion ...
Cardiovascular Research, Yellon, Derek M, Baxter, Gary F, Garcia-Dorado, David, Heusch, Gerd, Sumeray, Mark S
Methods and results In this study we verified the presence of mCx43 by a mass spectrometry-based proteomic approach in purified mitochondrial preparations from mouse myocardium and determined by ...
Cardiovascular Research, Miro-Casas, Elisabet, Ruiz-Meana, Marisol, Agullo, Esperanza, Stahlhofen, Sabine, RodrıÌguez-Sinovas, Antonio, Cabestrero, Alberto, Jorge, Inmaculada, Torre, Iratxe, ...