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Ehjcardiovascrec

[...]the coronary microcirculation is also a target of both injury by myocardial ischaemia/reperfusion and protection from it. Starting with Jim Downey's original observation of a causal role for ...

Cardiovascular Research, Heusch, Gerd, Kleinbongard, Petra, Skyschally, Andreas, Levkau, Bodo, Schulz, Rainer, Erbel, Raimund

Date : 01/05/2012 Item size : 528789 bytes
Ehjcardiovascrec

The signal transduction for protection from lethal reperfusion injury is still under intense debate.18 Yellon et al. have identified a concerted program of intracellular protein kinase activation ...

Cardiovascular Research, Heusch, Gerd

Date : 01/11/2009 Item size : 197656 bytes
Ehjcardiovascrec

Ischaemic pre and postconditioning are powerful cardioprotective phenomena, in which infarct size is reduced by one or several short episodes of myocardial ischaemia with reperfusion preceding or ...

Cardiovascular Research, Boengler, Kerstin, Schulz, Rainer, Heusch, Gerd

Date : 15/07/2009
Ehjcardiovascrec

Inhibition of the Na+/H+ exchanger attenuates the deterioration of ventricular function during pacing-induced heart failure in rabbits In sham rabbits treated with placebo (n=9) or BIIB722 (30 ...

Cardiovascular Research, Aker, Stephanie, Snabaitis, Andrew K, Konietzka, Ina, van de Sand, Anita, Böngler, Kerstin, Avkiran, Metin, Heusch, Gerd, Schulz, Rainer

Date : 01/08/2004 Item size : 315726 bytes
Ehjcardiovascrec

During the last three decades, a wide variety of ischaemic conditioning strategies and pharmacological treatments have been tested in the clinichowever, their translation from experimental to ...

Cardiovascular Research, Hausenloy, Derek J., Garcia-Dorado, David, Bøtker, Hans Erik, Davidson, Sean M., Downey, James, Engel, Felix B., Jennings, Robert, Lecour, Sandrine, Leor, Jonathan, ...

Date : 01/05/2017
Ehjcardiovascrec

Cardioprotection is a relatively vague term which more specifically refers to all interventions that reduce myocardial ischemia/reperfusion injury.1 In experimental animals, the most robust endpoint ...

Cardiovascular Research, Heusch, Gerd

Date : 01/11/2015
Ehjcardiovascrec

Because of this, there is currently no effective therapy for protecting the heart against the detrimental effects of acute IRI in patients with CHD. According to the World Health Organisation (WHO), ...

Cardiovascular Research, Hausenloy, Derek J., Bøtker, Hans Erik, Condorelli, Gianluigi, Ferdinandy, Peter, Garcia-Dorado, David, Heusch, Gerd, Lecour, Sandrine, van Laake, Linda W., Madonna, ...

Date : 01/04/2013
Ehjcardiovascrec

Acute myocardial infarction remains a significant health problem throughout the world, and for those patients surviving the immediate event, infarct size is the main determinant of further ...

Cardiovascular Research, Heusch, Gerd, Schulz, Rainer

Date : 01/10/2009 Item size : 275490 bytes
Ehjcardiovascrec

Acute myocardial infarction remains a significant health problem throughout the world, and for those patients surviving the immediate event, infarct size is the main determinant of further ...

Cardiovascular Research, Heusch, Gerd, Schulz, Rainer

Date : 01/10/2009 Item size : 290822 bytes
Ehjcardiovascrec

Ischaemic pre and postconditioning are powerful cardioprotective phenomena, in which infarct size is reduced by one or several short episodes of myocardial ischaemia with reperfusion preceding or ...

Cardiovascular Research, Boengler, Kerstin, Schulz, Rainer, Heusch, Gerd

Date : 15/07/2009 Item size : 675118 bytes