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Ehjcardiovascrec

The dystrophin gene encodes an essential component of the transmembrane dystrophinglycoprotein complex (DGC), which plays a critical role in maintaining membrane stability in cardiac and skeletal ...

Cardiovascular Research, Bauer, Ralf, Katus, Hugo A., Müller, Oliver J.

Date : 01/02/2010 Item size : 150661 bytes
Ehjcardiovascrec

Methods and results We report here that miR-223 is expressed in the murine lung and right ventricle at higher levels than in the left ventricle. [...]lung and right-ventricular miR-223 levels were ...

Cardiovascular Research, Shi, Lei, Kojonazarov, Baktybek, Elgheznawy, Amro, Popp, Rüdiger, Dahal, Bhola Kumar, Böhm, Mario, Pullamsetti, Soni Savai, Ghofrani, Hossein-Ardeschir, Gödecke, ...

Date : 01/08/2016
Ehjcardiovascrec

Introduction Human cardiomyopathy is considered to be a genetic disorder, and over 40 disease-causing mutations have been identified in patients and model systems. In clinical practice, ...

Cardiovascular Research, Ivandic, Boris T., Mastitsky, Sergey E., Schönsiegel, Frank, Bekeredjian, Raffi, Eils, Roland, Frey, Norbert, Katus, Hugo A., Brors, Benedikt

Date : 01/04/2012
Ehjcardiovascrec

[...]hERG currents in stably transfected human embryonic kidney (HEK 293) cells, native IKr currents and action potentials in isolated guinea pig ventricular cardiomyocytes were recorded using ...

Cardiovascular Research, Thomas, Dierk, Hammerling, Bettina C., Wimmer, Anna-Britt, Wu, Kezhong, Ficker, Eckhard, Kuryshev, Yuri A., Scherer, Daniel, Kiehn, Johann, Katus, Hugo A., Schoels, Wolfgang, ...

Date : 01/12/2004 Item size : 318089 bytes
Ehjcardiovascrec

Abstract Objective: Hereditary long QT syndrome (LQTS) is a genetically heterogeneous disease characterized by prolonged QT intervals and an increased risk for ventricular arrhythmias and sudden ...

Cardiovascular Research, Thomas, Dierk, Wimmer, Anna-Britt, Karle, Christoph A., Licka, Manuela, Alter, Markus, Khalil, Markus, Ulmer, Herbert E., Kathöfer, Sven, Kiehn, Johann, Katus, Hugo A., ...

Date : 15/08/2005 Item size : 291855 bytes
Ehjcardiovascrec

Adenosine inhibits norepinephrine release in the postischemic rat heart: the mechanism of neuronal stunning Results are expressed as mean S2/S1 ratios±S.E.M. Stepwise increase of global ischemic ...

Cardiovascular Research, Burgdorf, Christof, Richardt, Doreen, Kurz, Thomas, Seyfarth, Melchior, Jain, Deepak, Katus, Hugo A., Richardt, Gert

Date : 01/03/2001
Ehjcardiovascrec

Within atherosclerotic lesions, Egr-1 is expressed in smooth muscle cells, endothelial cells, and macrophages. Since macrophages play a pivotal role in atherosclerotic lesion initiation and ...

Cardiovascular Research, Albrecht, Claudia, Preusch, Michael R., Hofmann, Götz, Morris-Rosenfeld, Samuel, Blessing, Erwin, Rosenfeld, Michael E., Katus, Hugo A., Bea, Florian

Date : 01/05/2010 Item size : 285791 bytes
Ehjcardiovascrec

Abstract Objective: Adrenergic stimulation of the heart leads to activation of the phospholipase D signal transduction pathway with formation of the intracellular second messengers phosphatidic acid ...

Cardiovascular Research, Mier, Kenneth, Kemken, Dorit, Katus, Hugo A., Richardt, Gert, Kurz, Thomas

Date : 01/04/2002
Ehjcardiovascrec

Transgenic rat hearts expressing a human cardiac troponin T deletion reveal diastolic dysfunction and ventricular arrhythmias Abstract Objective: Familial hypertrophic cardiomyopathy (FHC) due to ...

Cardiovascular Research, Frey, Norbert, Franz, Wolfgang M., Gloeckner, Katharina, Degenhardt, Michael, Müller, Matthias, Müller, Oliver, Merz, Hartmut, Katus, Hugo A.

Date : 01/08/2000
Ehjcardiovascrec

Abstract Objective: Patients with HERG-associated long QT syndrome typically develop tachyarrhythmias during physical or emotional stress. Previous studies have revealed that activation of the ...

Cardiovascular Research, Thomas, Dierk, Zhang, Wei, Wu, Kezhong, Wimmer, Anna-Britt, Gut, Bernd, Wendt-Nordahl, Gunnar, Kathöfer, Sven, Kreye, Volker A.W., Katus, Hugo A., Schoels, Wolfgang, ...

Date : 01/07/2003 Item size : 353260 bytes