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Methods: Regional differences in action potential duration (APD) and E-4031-sensitive component (IKr) as well as -insensitive component (IKs) of the delayed rectifier K+ current (IK) were ...

Cardiovascular Research, Cheng, Jianhua, Kamiya, Kaichiro, Liu, Weiran, Tsuji, Yukiomi, Toyama, Junji, Kodama, Itsuo

Date : 01/07/1999

Numerical simulations using 3D atrial geometries (Courtemanche-Ramirez-Nattel human atrial model) predicted that, similar to experiments, filaments of meandering ASWs stabilized at locations with ...

Cardiovascular Research, Yamazaki, Masatoshi, Mironov, Sergey, Taravant, Clément, Brec, Julien, Vaquero, Luis M., Bandaru, Krishna, Avula, Uma Mahesh R, Honjo, Haruo, Kodama, Itsuo, Berenfeld, ...

Date : 01/04/2012

Abstract Objectives: Loss of cardiac cells and the anatomical or functional remodeling of intercellular coupling occur under several pathological conditions. Treatment of the cultured myocytes at ...

Cardiovascular Research, Yasui, Kenji, Kada, Kenji, Hojo, Mayumi, Lee, Jong-Kook, Kamiya, Kaichiro, Toyama, Junji, Opthof, Tobias, Kodama, Itsuo

Date : 01/10/2000 Item size : 270324 bytes

Abstract Objectives: Cardiac hypertrophy is characterized by a prolongation of action potential duration (APD) and a reduction of outward K+ currents, primarily the transient outward current ...

Cardiovascular Research, Guo, Weinong, Kamiya, Kaichiro, Yasui, Kenji, Kodama, Itsuo, Toyama, Junji

Date : 01/01/1999 Item size : 257954 bytes

Methods: Extracellular potentials were recorded from the endocardial surface of the SA node in isolated right atrial preparations of rabbits through custom-made modified bipolar electrodes with ...

Cardiovascular Research, Yamamoto, Mitsuru, Honjo, Haruo, Niwa, Ryoko, Kodama, Itsuo

Date : 01/08/1998 Item size : 309727 bytes

Objective: In a computer simulation study to mimic cardiac action potential, the total open time of the sodium channel at each excitation has been shown by other authors to be longer during ...

Cardiovascular Research, Iida, Masato, Kodama, Itsuo, Toyama, Junji

Date : 01/04/1996 Item size : 96949 bytes

If analogous Cx43 up-regulation is induced in the diseased heart, it would provide a new perspective in radiation therapy for arrhythmias. Methods: Non-transmural myocardial infarction (MI) was ...

Cardiovascular Research, Amino, Mari, Yoshioka, Koichiro, Tanabe, Teruhisa, Tanaka, Etsuro, Mori, Hidezo, Furusawa, Yoshiya, Zareba, Wojciech, Yamazaki, Masatoshi, Nakagawa, Harumichi, Honjo, Haruo, ...

Date : 01/12/2006 Item size : 291372 bytes

Pacing-induced heart failure causes a reduction of delayed rectifier potassium currents along with decreases in calcium and transient outward currents in rabbit ventricle Abstract Objective: Heart ...

Cardiovascular Research, Tsuji, Yukiomi, Opthof, Tobias, Kamiya, Kaichiro, Yasui, Kenji, Liu, Weiran, Lu, Zhibo, Kodama, Itsuo

Date : 01/11/2000 Item size : 333021 bytes

Abstract Aims The aim of this study was to investigate the role of gap junctions in atrial fibrillation (AF) by analysing the effects of a gap junction enhancer and blocker on AF vulnerability and ...

Cardiovascular Research, Ueda, Norihiro, Yamamoto, Mitsuru, Honjo, Haruo, Kodama, Itsuo, Kamiya, Kaichiro

Date : 01/11/2014 Item size : 225514 bytes

The Cardiac Arrhythmia Suppression Trial (CAST) reported the harmful effects of flecainide, encainide and moricizine in patients with ventricular premature beats who had had myocardial infarction ...

Cardiovascular Research, Kodama, Itsuo, Kamiya, Kaichiro, Toyama, Junji

Date : 01/07/1997 Item size : 730772 bytes