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Ehjcardiovascrec

Calmodulin/CaMKII inhibition improves intercellular communication and impulse propagation in the heart and is antiarrhythmic under conditions when fibrosis is absent AimIn healthy hearts, ...

Cardiovascular Research, Takanari, Hiroki, Bourgonje, Vincent J.A., Fontes, Magda S.C., Raaijmakers, Antonia J.A., Driessen, Helen, Jansen, John A., van der Nagel, Roel, Kok, Bart, van Stuijvenberg, ...

Date : 01/09/2016 Item size : 168750 bytes
Ehjcardiovascrec

Too much electrical coupling will turn the SA node silent, because its membrane will be clamped to a more negative potential than the normal maximal diastolic potential despite its intrinsic ...

Cardiovascular Research, Honjo, Haruo, Boyett, Mark R, Coppen, Steven R, Takagishi, Yoshiko, Opthof, Tobias, Severs, Nicholas J, Kodama, Itsuo

Date : 01/01/2002
Ehjcardiovascrec

Abstract Aims The aim of this study was to investigate the role of gap junctions in atrial fibrillation (AF) by analysing the effects of a gap junction enhancer and blocker on AF vulnerability and ...

Cardiovascular Research, Ueda, Norihiro, Yamamoto, Mitsuru, Honjo, Haruo, Kodama, Itsuo, Kamiya, Kaichiro

Date : 01/11/2014
Ehjcardiovascrec

If analogous Cx43 up-regulation is induced in the diseased heart, it would provide a new perspective in radiation therapy for arrhythmias. Methods: Non-transmural myocardial infarction (MI) was ...

Cardiovascular Research, Amino, Mari, Yoshioka, Koichiro, Tanabe, Teruhisa, Tanaka, Etsuro, Mori, Hidezo, Furusawa, Yoshiya, Zareba, Wojciech, Yamazaki, Masatoshi, Nakagawa, Harumichi, Honjo, Haruo, ...

Date : 01/12/2006 Item size : 316514 bytes
Ehjcardiovascrec

Abstract AimIn healthy hearts, ventricular gap junctions are mainly composed by connexin43 (Cx43) and localize in the intercalated disc, enabling appropriate electrical coupling. Reduced expression ...

Cardiovascular Research, Takanari, Hiroki, Bourgonje, Vincent J.A., Fontes, Magda S.C., Raaijmakers, Antonia J.A., Driessen, Helen, Jansen, John A., van der Nagel, Roel, Kok, Bart, van Stuijvenberg, ...

Date : 01/09/2016 Item size : 402408 bytes
Ehjcardiovascrec

Methods: In the atria of the rat, the localisation of HCN4 and connexins was determined using immunohistochemistry, and electrical activity was recorded using extracellular electrodes. The same ...

Cardiovascular Research, Yamamoto, Mitsuru, Dobrzynski, Halina, Tellez, James, Niwa, Ryoko, Billeter, Rudi, Honjo, Haruo, Kodama, Itsuo, Boyett, Mark R.

Date : 01/11/2006
Ehjcardiovascrec

Methods: Extracellular potentials were recorded from the endocardial surface of the SA node in isolated right atrial preparations of rabbits through custom-made modified bipolar electrodes with ...

Cardiovascular Research, Yamamoto, Mitsuru, Honjo, Haruo, Niwa, Ryoko, Kodama, Itsuo

Date : 01/08/1998 Item size : 306456 bytes
Ehjcardiovascrec

In UM-X7.1 hamsters, olmesartan improved abnormal ID ultrastructural changes, attenuated the decrease of total cellular and nuclear β-catenin expression, decreased VT/VF induction, and improved ...

Cardiovascular Research, Yoshida, Masaaki, Ohkusa, Tomoko, Nakashima, Tadamitsu, Takanari, Hiroki, Yano, Masafumi, Takemura, Genzou, Honjo, Haruo, Kodama, Itsuo, Mizukami, Yoichi, Matsuzaki, Masunori

Date : 01/10/2011
Ehjcardiovascrec

Numerical simulations using 3D atrial geometries (Courtemanche-Ramirez-Nattel human atrial model) predicted that, similar to experiments, filaments of meandering ASWs stabilized at locations with ...

Cardiovascular Research, Yamazaki, Masatoshi, Mironov, Sergey, Taravant, Clément, Brec, Julien, Vaquero, Luis M., Bandaru, Krishna, Avula, Uma Mahesh R, Honjo, Haruo, Kodama, Itsuo, Berenfeld, ...

Date : 01/04/2012
Ehjcardiovascrec

Methods: Extracellular potentials were recorded from the endocardial surface of the SA node in isolated right atrial preparations of rabbits through custom-made modified bipolar electrodes with ...

Cardiovascular Research, Yamamoto, Mitsuru, Honjo, Haruo, Niwa, Ryoko, Kodama, Itsuo

Date : 01/08/1998 Item size : 309727 bytes