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Ehjcardiovascrec

Differential effects of MS-551 and E-4031 on action potentials and the delayed rectifier K+ current in rabbit ventricular myocytes

Cardiovascular Research, Cheng, Jianhua, Kamiya, Kaichiro, Kodama, Itsuo, Toyama, Junji

Date : 01/06/1996
Ehjcardiovascrec

Calmodulin/CaMKII inhibition improves intercellular communication and impulse propagation in the heart and is antiarrhythmic under conditions when fibrosis is absent AimIn healthy hearts, ...

Cardiovascular Research, Takanari, Hiroki, Bourgonje, Vincent J.A., Fontes, Magda S.C., Raaijmakers, Antonia J.A., Driessen, Helen, Jansen, John A., van der Nagel, Roel, Kok, Bart, van Stuijvenberg, ...

Date : 01/09/2016 Item size : 168750 bytes
Ehjcardiovascrec

Abstract Aims The aim of this study was to investigate the role of gap junctions in atrial fibrillation (AF) by analysing the effects of a gap junction enhancer and blocker on AF vulnerability and ...

Cardiovascular Research, Ueda, Norihiro, Yamamoto, Mitsuru, Honjo, Haruo, Kodama, Itsuo, Kamiya, Kaichiro

Date : 01/11/2014
Ehjcardiovascrec

If analogous Cx43 up-regulation is induced in the diseased heart, it would provide a new perspective in radiation therapy for arrhythmias. Methods: Non-transmural myocardial infarction (MI) was ...

Cardiovascular Research, Amino, Mari, Yoshioka, Koichiro, Tanabe, Teruhisa, Tanaka, Etsuro, Mori, Hidezo, Furusawa, Yoshiya, Zareba, Wojciech, Yamazaki, Masatoshi, Nakagawa, Harumichi, Honjo, Haruo, ...

Date : 01/12/2006 Item size : 316514 bytes
Ehjcardiovascrec

Abstract Objectives: Loss of cardiac cells and the anatomical or functional remodeling of intercellular coupling occur under several pathological conditions. Treatment of the cultured myocytes at ...

Cardiovascular Research, Yasui, Kenji, Kada, Kenji, Hojo, Mayumi, Lee, Jong-Kook, Kamiya, Kaichiro, Toyama, Junji, Opthof, Tobias, Kodama, Itsuo

Date : 01/10/2000 Item size : 285426 bytes
Ehjcardiovascrec

Abstract AimIn healthy hearts, ventricular gap junctions are mainly composed by connexin43 (Cx43) and localize in the intercalated disc, enabling appropriate electrical coupling. Reduced expression ...

Cardiovascular Research, Takanari, Hiroki, Bourgonje, Vincent J.A., Fontes, Magda S.C., Raaijmakers, Antonia J.A., Driessen, Helen, Jansen, John A., van der Nagel, Roel, Kok, Bart, van Stuijvenberg, ...

Date : 01/09/2016 Item size : 402408 bytes
Ehjcardiovascrec

Abstract Objectives: Cardiac hypertrophy is characterized by a prolongation of action potential duration (APD) and a reduction of outward K+ currents, primarily the transient outward current ...

Cardiovascular Research, Guo, Weinong, Kamiya, Kaichiro, Yasui, Kenji, Kodama, Itsuo, Toyama, Junji

Date : 01/01/1999 Item size : 284134 bytes
Ehjcardiovascrec

Abstract Aims Long QT syndrome (LQTS) is an inheritable and life-threatening disease; however, it is often difficult to determine disease characteristics in sporadic cases with novel mutations, and ...

Cardiovascular Research, Egashira, Toru, Yuasa, Shinsuke, Suzuki, Tomoyuki, Aizawa, Yoshiyasu, Yamakawa, Hiroyuki, Matsuhashi, Tomohiro, Ohno, Yohei, Tohyama, Shugo, Okata, Shinichiro, Seki, ...

Date : 01/09/2012 Item size : 348491 bytes
Ehjcardiovascrec

Pacing-induced heart failure causes a reduction of delayed rectifier potassium currents along with decreases in calcium and transient outward currents in rabbit ventricle Abstract Objective: Heart ...

Cardiovascular Research, Tsuji, Yukiomi, Opthof, Tobias, Kamiya, Kaichiro, Yasui, Kenji, Liu, Weiran, Lu, Zhibo, Kodama, Itsuo

Date : 01/11/2000
Ehjcardiovascrec

The Cardiac Arrhythmia Suppression Trial (CAST) reported the harmful effects of flecainide, encainide and moricizine in patients with ventricular premature beats who had had myocardial infarction ...

Cardiovascular Research, Kodama, Itsuo, Kamiya, Kaichiro, Toyama, Junji

Date : 01/07/1997