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Ehjcardiovascrec

Abstract Background: We have shown that rapid atrial activation, as occurs during atrial fibrillation (AF), reduces L-type Ca2+ current (ICa) and that this is the principal mechanism of the action ...

Cardiovascular Research, Original Article, Rania Gaspo, Hui Sun, Samir Fareh, Mirie Levi, Lixia Yue, Bruce G. Allen, Terence E. Hebert, Stanley Nattel

Date : 01/05/1999 Item size : 258753 bytes
Ehjcardiovascrec

In disease states, fibroblast production of increased quantities of ECM proteins leads to tissue fibrosis, which can impair both mechanical and electrical function of the heart, contributing to heart ...

Cardiovascular Research, REVIEWS: FOCUS ON THE MOLECULAR BASIS OF ATRIAL FIBRILLATION, Lixia Yue, Jia Xie, Stanley Nattel

Date : 01/03/2011 Item size : 519835 bytes
Ehjcardiovascrec

Methods: Standard whole-cell patch clamp techniques were used to study the effects of multiple concentrations of each drug. The magnitude of voltage-dependent block was directly related to the ...

Cardiovascular Research, Original Article, Lixia Yue, Jian Lin Feng, Zhiguo Wang, Stanley Nattel

Date : 01/04/2000