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Ehjcardiovascrec

Abstract Aims Impaired repolarization in cardiac myocytes can lead to long QT syndrome (LQTS), with delayed repolarization and increased susceptibility to Torsades de Pointes (TdP) ...

Cardiovascular Research, Original Article, Thomas G. Diness, Yung-Hsin Yeh, Xiao Yan Qi, Denis Chartier, Yukiomi Tsuji, Rie S. Hansen, Soren-Peter Olesen, Morten Grunnet, Stanley Nattel

Date : 01/07/2008
Ehjcardiovascrec

Atrial cellular arrhythmia mechanisms have not been defined in congenital LQTS. [...]we studied atrial cardiomyocyte electrophysiology in mice with an LQTS3 SCN5A inactivation-impairing mutation ...

Cardiovascular Research, Original Article, Marc D. Lemoine, James Elber Duverger, Patrice Naud, Denis Chartier, Xiao Yan Qi, Philippe Comtois, Larissa Fabritz, Paulus Kirchhof, Stanley Nattel

Date : 01/10/2011
Ehjcardiovascrec

After initial dismissal of a functional role for SK channels in the heart,1 a series of elegant studies from the Chiamvimonvat laboratory rekindled interest,2,3 as did subsequent work suggesting that ...

Cardiovascular Research, Editorial, Stanley Nattel, Xiao Yan Qi

Date : 01/02/2014