top
Search terms
Results 1 - 10 of 11 - ordered by :
Pages: 1 2
Ehjcardiovascrec

Abstract Background: We have shown that rapid atrial activation, as occurs during atrial fibrillation (AF), reduces L-type Ca2+ current (ICa) and that this is the principal mechanism of the action ...

Cardiovascular Research, Original Article, Rania Gaspo, Hui Sun, Samir Fareh, Mirie Levi, Lixia Yue, Bruce G. Allen, Terence E. Hebert, Stanley Nattel

Date : 01/05/1999 Item size : 258753 bytes
Ehjcardiovascrec

Not only do disease states affect the determinants of cardiac electrical function in profound ways, but we now recognise that cardiac arrhythmias can themselves produce profound changes in the ...

Cardiovascular Research, Editorial, Stanley Nattel, Dan M. Roden, Denis Escande

Date : 01/05/1999 Item size : 177552 bytes
Ehjcardiovascrec

[...]GPA prolonged atrial refractory period and decreased AF vulnerability (75 ± 8 to 30 ± 10%, P< 0.05), AF duration (617 ± 246 to 39 ± 23 s, **P< 0.01), and DF (11.4 ± 0.6 to 8.6 ...

Cardiovascular Research, ORIGINAL ARTICLES: FOCUS ON THE MOLECULAR BASIS OF ATRIAL FIBRILLATION, Kunihiro Nishida, Ange Maguy, Masao Sakabe, Philippe Comtois, Hiroshi Inoue, Stanley Nattel

Date : 01/03/2011
Ehjcardiovascrec

Results: Mean duration of burst-pacing induced AF was similar in placebo (567±203 s) and diltiazem-treated (963±280 s, P = NS) animals, but was much less in mibefradil-treated dogs (3.6±0.9 ...

Cardiovascular Research, Original Article, Samir Fareh, Agnès Bénardeau, Stanley Nattel

Date : 01/03/2001
Ehjcardiovascrec

Abstract Background: There is evidence suggesting involvement of oxidative stress, inflammation, and calcineurin/nuclear factor of activated T cell pathways in atrial fibrillation. Dogs were ...

Cardiovascular Research, Original Article, Akiko Shiroshita-Takeshita, Bianca J.J.M. Brundel, Joel Lavoie, Stanley Nattel

Date : 01/03/2006
Ehjcardiovascrec

Abstract Aims Although atrial tachycardia (AT) remodelling promotes agonist-independent, constitutively active, acetylcholine-regulated K+-current (IK,ACh) that increases susceptibility to atrial ...

Cardiovascular Research, RAPID COMMUNICATION, Niels Voigt, Ange Maguy, Yung-Hsin Yeh, Xiaoyan Qi, Ursula Ravens, Dobromir Dobrev, Stanley Nattel

Date : 01/01/2008
Ehjcardiovascrec

Methods: Intracellular Ca2+ transients (CaT) and cell shortening (CS) were measured by microfluorometry (Indo-1 AM) and video edge-detection in isolated, field-stimulated canine atrial myocytes ...

Cardiovascular Research, Original Article, Hui Sun, Denis Chartier, Normand Leblanc, Stanley Nattel

Date : 01/03/2001
Ehjcardiovascrec

Abstract One of the most exciting developments in our understanding of atrial fibrillation (AF) over the last several years has been the recognition that AF itself modifies atrial electrical ...

Cardiovascular Research, Review, Stanley Nattel

Date : 01/05/1999
Ehjcardiovascrec

Ionic targets for drug therapy and atrial fibrillation-induced electrical remodeling: insights from a mathematical model Objectives: Using a mathematical model of the human atrial action potential ...

Cardiovascular Research, Original Article, Marc Courtemanche, Rafael J Ramirez, Stanley Nattel

Date : 01/05/1999
Ehjcardiovascrec

Atrial fibrillation (AF), the most common sustained arrhythmia, is associated with substantial cardiovascular morbidity and mortality, with stroke being the most critical complication.1 Present drugs ...

Cardiovascular Research, EDITORIAL: FOCUS ON THE MOLECULAR BASIS OF ATRIAL FIBRILLATION, Dobromir Dobrev, Stanley Nattel

Date : 01/03/2011