Enalapril effects on atrial remodeling and atrial fibrillation in experimental congestive heart failure There is evidence that angiotensin-converting enzyme (ACE) inhibitors reduce the prevalence of ...
Cardiovascular Research, Original Article, Yanfen Shi, Danshi Li, Jean-Claude Tardif, Stanley Nattel
Here, we assessed the differential expression of Kv currents between atrial and ventricular fibroblasts from control dogs and dogs with an atrial arrhythmogenic substrate caused by congestive heart ...
Cardiovascular Research, Ion channels and arrhythmias, Chia-Tung Wu, Xiao-Yan Qi, Hai Huang, Patrice Naud, Kristin Dawson, Yung-Hsin Yeh, Masahide Harada, Chi-Tai Kuo, Stanley Nattel
The identification of the molecular structure of many ion channels involved in cardiac excitability and their functional correlation with native ionic currents have made it possible to study the ...
Cardiovascular Research, Review, Ralph F Bosch, Stanley Nattel
[...]GPA prolonged atrial refractory period and decreased AF vulnerability (75 ± 8 to 30 ± 10%, P< 0.05), AF duration (617 ± 246 to 39 ± 23 s, **P< 0.01), and DF (11.4 ± 0.6 to 8.6 ...
Cardiovascular Research, ORIGINAL ARTICLES: FOCUS ON THE MOLECULAR BASIS OF ATRIAL FIBRILLATION, Kunihiro Nishida, Ange Maguy, Masao Sakabe, Philippe Comtois, Hiroshi Inoue, Stanley Nattel
Differences in atrial versus ventricular remodeling in dogs with ventricular tachypacing-induced congestive heart failure Abstract Background: Congestive heart failure (CHF) causes arrhythmogenic ...
Cardiovascular Research, Original Article, Nessrine Hanna, Sophie Cardin, Tack-Ki Leung, Stanley Nattel
Evolution of the atrial fibrillation substrate in experimental congestive heart failure: angiotensin-dependent and -independent pathways Protein expression was determined by Western blot, ...
Cardiovascular Research, Original Article, Sophie Cardin, Danshi Li, Nathalie Thorin-Trescases, Tack-Ki Leung, Eric Thorin, Stanley Nattel
Effects of simvastatin on the development of the atrial fibrillation substrate in dogs with congestive heart failure Abstract Background: Congestive heart failure (CHF) is a common cause of atrial ...
Cardiovascular Research, Original Article, Akiko Shiroshita-Takeshita, Bianca J.J.M. Brundel, Brett Burstein, Tack-Ki Leung, Hideo Mitamura, Satoshi Ogawa, Stanley Nattel
In cardiac disease states such as heart failure and atrial fibrillation (AF), changes in ion channel properties appear as part of an adaptive response to maintain function in the face of ...
Cardiovascular Research, Review, Georghia Michael, Ling Xiao, Xiao-Yan Qi, Dobromir Dobrev, Stanley Nattel
Little is known about the expression of corresponding hyperpolarization-activated cyclic nucleotide-gated (HCN) channel subunits in normal hearts and HCN remodeling by diseases, like congestive heart ...
Cardiovascular Research, Original Article, Stephen Zicha, MarÃa Fernández-Velasco, Giuseppe Lonardo, Nathalie L'Heureux, Stanley Nattel