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AF is responsible for considerable morbidity and medical costs [1], is a major determinant of stroke [2] and may increase mortality, particularly in patients with congestive heart failure (CHF) ...

Cardiovascular Research, Review, Stanley Nattel

Date : 01/05/2002 Item size : 622256 bytes

Not only do disease states affect the determinants of cardiac electrical function in profound ways, but we now recognise that cardiac arrhythmias can themselves produce profound changes in the ...

Cardiovascular Research, Editorial, Stanley Nattel, Dan M. Roden, Denis Escande

Date : 01/05/1999 Item size : 177552 bytes

The identification of the molecular structure of many ion channels involved in cardiac excitability and their functional correlation with native ionic currents have made it possible to study the ...

Cardiovascular Research, Review, Ralph F Bosch, Stanley Nattel

Date : 01/05/2002 Item size : 503601 bytes

Ventricular dysfunction due to a rapid response to AF can cause structural remodeling, but whether AF itself directly promotes atrial fibrosis is controversial. 2 Methods 2.1 Cardiomyocyte culture ...

Cardiovascular Research, Original Article, Brett Burstein, Xiao-Yan Qi, Yung-Hsin Yeh, Angelino Calderone, Stanley Nattel

Date : 01/12/2007

Methods: Dogs were subjected to atrial-tachypacing (400 bpm) for 7 days during treatment with 240 mg/day (standard clinical dose) of the NHE1 inhibitor cariporide (CariL, n=6), 1000 mg/day cariporide ...

Cardiovascular Research, Original Article, Kaori Shinagawa, Hideo Mitamura, Satoshi Ogawa, Stanley Nattel

Date : 01/05/2002

Ionic targets for drug therapy and atrial fibrillation-induced electrical remodeling: insights from a mathematical model Objectives: Using a mathematical model of the human atrial action potential ...

Cardiovascular Research, Original Article, Marc Courtemanche, Rafael J Ramirez, Stanley Nattel

Date : 01/05/1999