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Results: Verapamil caused AF promotion in six dogs, increasing mean duration of AF induced by burst pacing, from 8±4 s (mean±S.E.) to 95±39 s (P<0.01 vs. control) at a loading dose of 0.1 ...

Cardiovascular Research, Original Article, Agnès Bénardeau, Samir Fareh, Stanley Nattel

Date : 01/04/2001 Item size : 252007 bytes

Introduction Atrial fibrillation (AF) is a common cardiac arrhythmia associated with increased cardiovascular morbidity and mortality.13 Conventional anti-arrhythmic drugs often fail to provide ...

Cardiovascular Research, Original Article, Masao Sakabe, Akiko Shiroshita-Takeshita, Ange Maguy, Bianca J.J.M. Brundel, Akira Fujiki, Hiroshi Inoue, Stanley Nattel

Date : 01/04/2008

Results: Mean duration of burst-pacing induced AF was similar in placebo (567±203 s) and diltiazem-treated (963±280 s, P = NS) animals, but was much less in mibefradil-treated dogs (3.6±0.9 ...

Cardiovascular Research, Original Article, Samir Fareh, Agnès Bénardeau, Stanley Nattel

Date : 01/03/2001

Methods: Dogs were subjected to atrial-tachypacing (400 bpm) for 7 days during treatment with 240 mg/day (standard clinical dose) of the NHE1 inhibitor cariporide (CariL, n=6), 1000 mg/day cariporide ...

Cardiovascular Research, Original Article, Kaori Shinagawa, Hideo Mitamura, Satoshi Ogawa, Stanley Nattel

Date : 01/05/2002

No change in ERP or AF duration occurred at 160 bpm. Because of the limited effects of 200 bpm ATP on AF duration despite significant effects on ERP, we tested 200 bpm ATP effects in the presence of ...

Cardiovascular Research, Original Article, Akiko Shiroshita-Takeshita, Hideo Mitamura, Satoshi Ogawa, Stanley Nattel

Date : 01/01/2009