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Here, we assessed the differential expression of Kv currents between atrial and ventricular fibroblasts from control dogs and dogs with an atrial arrhythmogenic substrate caused by congestive heart ...

Cardiovascular Research, Ion channels and arrhythmias, Chia-Tung Wu, Xiao-Yan Qi, Hai Huang, Patrice Naud, Kristin Dawson, Yung-Hsin Yeh, Masahide Harada, Chi-Tai Kuo, Stanley Nattel

Date : 01/06/2014 Item size : 319683 bytes

Atrial cellular arrhythmia mechanisms have not been defined in congenital LQTS. [...]we studied atrial cardiomyocyte electrophysiology in mice with an LQTS3 SCN5A inactivation-impairing mutation ...

Cardiovascular Research, Original Article, Marc D. Lemoine, James Elber Duverger, Patrice Naud, Denis Chartier, Xiao Yan Qi, Philippe Comtois, Larissa Fabritz, Paulus Kirchhof, Stanley Nattel

Date : 01/10/2011

Methods: Intracellular Ca2+ transients (CaT) and cell shortening (CS) were measured by microfluorometry (Indo-1 AM) and video edge-detection in isolated, field-stimulated canine atrial myocytes ...

Cardiovascular Research, Original Article, Hui Sun, Denis Chartier, Normand Leblanc, Stanley Nattel

Date : 01/03/2001

Methods: Standard whole-cell patch clamp techniques were used to study the effects of multiple concentrations of each drug. The magnitude of voltage-dependent block was directly related to the ...

Cardiovascular Research, Original Article, Lixia Yue, Jian Lin Feng, Zhiguo Wang, Stanley Nattel

Date : 01/04/2000

Methods: Expression and distribution of the inward-rectifier subunits Kir2.1 and Kir2.3, the rapid delayed-rectifier α-subunit ERG, the slow delayed-rectifier α-subunit KvLQT1, the β-subunit ...

Cardiovascular Research, Research Article, Peter Melnyk, Joachim R. Ehrlich, Marc Pourrier, Louis Villeneuve, Tae-Joon Cha, Stanley Nattel

Date : 01/01/2005