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Abstract Objective: Acute atrial ischemia produces a substrate for atrial fibrillation (AF) maintenance, but the response of this substrate to antiarrhythmic-drugs has not been defined. Isolated ...

Cardiovascular Research, Original Article, Lena Rivard, Hani Sinno, Akiko Shiroshita-Takeshita, Gernot Schram, Tack-Ki Leung, Stanley Nattel

Date : 01/04/2007

Background: Azimilide, a new class III drug, was initially believed to be a highly selective blocker of the slow delayed rectifier (IKs), but recent studies suggest that azimilide potently blocks ...

Cardiovascular Research, Original Article, Stanley Nattel, Lili Liu, Dalie St-Georges

Date : 01/03/1998

Abstract Objectives: This study evaluated the in vivo electrophysiological effects of a highly selective slow delayed-rectifier K+-current blocker, HMR 1556, to gain insights into the consequences of ...

Cardiovascular Research, Original Article, Hideko Nakashima, Uwe Gerlach, Dietmar Schmidt, Stanley Nattel

Date : 01/03/2004

KeywordsAntiarrhythmic agentsArrhythmia (mechanisms)Supraventricular arrhythmiaTime for primary review 34 days. 1 Introduction Atrial fibrillation (AF) is the most common sustained arrhythmia in ...

Cardiovascular Research, Original Article, Katayoun Derakhchan, Christine Villemaire, Mario Talajic, Stanley Nattel

Date : 01/04/2001