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Methods: We studied Ba2+ block of homo- and heteromeric Kir2 channels in Xenopus oocytes and compared the properties observed to those of human cardiac IK1 in cells isolated from myocardial biopsies ...

Cardiovascular Research, Original Article, Gernot Schram, Marc Pourrier, Zhiguo Wang, Michel White, Stanley Nattel

Date : 01/08/2003 Item size : 248553 bytes

Acquired delayed rectifier channelopathies: how heart disease and antiarrhythmic drugs mimic potentially-lethal congenital cardiac disorders The discovery of the molecular bases of the congenital ...

Cardiovascular Research, Editorial, Stanley Nattel

Date : 01/11/2000

Methods: Whole-cell patch clamp techniques were applied to assess the effects of 293B on isolated myocytes at 36°C. Results: Delayed rectifier current (IK) elicited by pulses to +60 mV from a ...

Cardiovascular Research, Original Article, Ralph F. Bosch, Rania Gaspo, Andreas E. Busch, Hans J. Lang, Gui-Rong Li, Stanley Nattel

Date : 01/05/1998