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Ehjcardiovascrec

The Hatter Institute for Cardiovascular Studies, Department of Academic Cardiology, University College and Middlesex Hospital, Gower Street, London WClE 6AU, United Kingdom: D M Yellon, A M ...

Cardiovascular Research, Yellon, Derek M, Alkhulaifi, Abdul M, Browne, Emma E, Pugsley, Wilf B

Date : 01/10/1992
Ehjcardiovascrec

[...]the effects of disease states on this HS-induced cytoprotective response are less known. [...]we investigated the effects of prior heat stress on the infarct size in the isolated heart and on ...

Cardiovascular Research, Joyeux, Marie, Faure, Patrice, Godin-Ribuot, Diane, Halimi, Serge, Patel, Asha, Yellon, Derek M, Demenge, Pierre, Ribuot, Christophe

Date : 01/09/1999
Ehjcardiovascrec

The phenomenon of ischaemic preconditioning, in which a period of sublethal ischemia can profoundly protect the cell from subsequent lethal ischemic insult, has without doubt been responsible for an ...

Cardiovascular Research, Yellon, Derek M, Downey, James M

Date : 15/08/2002 Item size : 205674 bytes
Ehjcardiovascrec

The potential for clinical application to benefit patients with a variety of pathological conditions has led to an expansion in our knowledge concerning the pathophysiology of ischemia-reperfusion ...

Cardiovascular Research, Yellon, Derek M, Baxter, Gary F, Garcia-Dorado, David, Heusch, Gerd, Sumeray, Mark S

Date : 01/01/1998 Item size : 605350 bytes
Ehjcardiovascrec

The potential for clinical application to benefit patients with a variety of pathological conditions has led to an expansion in our knowledge concerning the pathophysiology of ischemia-reperfusion ...

Cardiovascular Research, Yellon, Derek M, Baxter, Gary F, Garcia-Dorado, David, Heusch, Gerd, Sumeray, Mark S

Date : 01/01/1998 Item size : 548538 bytes
Ehjcardiovascrec

Abstract Objective: We propose that ischemic preconditioning (IPC) and mitochondrial KATP channel activation protect the myocardium by inhibiting mitochondrial permeability transition pore (MPTP) ...

Cardiovascular Research, Hausenloy, Derek J, Maddock, Helen L, Baxter, Gary F, Yellon, Derek M

Date : 15/08/2002 Item size : 295447 bytes
Ehjcardiovascrec

The phenomenon of ischaemic preconditioning, in which a period of sublethal ischemia can profoundly protect the cell from subsequent lethal ischemic insult, has without doubt been responsible for an ...

Cardiovascular Research, Yellon, Derek M, Downey, James M

Date : 15/08/2002 Item size : 179121 bytes
Ehjcardiovascrec

Abstract Background: Recent studies have postulated that mitochondrial ATP-sensitive potassium (mitoKATP) channel activation may modulate mitochondrial function with the resultant induction of a ...

Cardiovascular Research, Minners, Jan, van den Bos, Ewout J, Yellon, Derek M, Schwalb, Herzl, Opie, Lionel H, Sack, Michael N

Date : 01/07/2000
Ehjcardiovascrec

Therapeutic strategies that target and attenuate reperfusion-induced cell death may provide novel pharmacological agents, which can be used as an adjunct to current reperfusion therapy, to limit ...

Cardiovascular Research, Hausenloy, Derek J, Yellon, Derek M

Date : 15/02/2004 Item size : 559838 bytes
Ehjcardiovascrec

Conclusion: These results demonstrate for the first time that the mitoKATP channel opener diazoxide can act as a trigger of preconditioning by a mechanism involving mitochondrial swelling and the ...

Cardiovascular Research, Carroll, Richard, Gant, Vanya A, Yellon, Derek M

Date : 01/09/2001 Item size : 283733 bytes