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Ehjcardiovascrec

Under differentiation conditions (i.e. in the absence of dox), the cells stopped dividing and spontaneously reacquired a phenotype very similar to that of primary AMs (pAMs) in gene expression ...

Cardiovascular Research, Liu, Jia, Volkers, Linda, Jangsangthong, Wanchana, Bart, Cindy I, Engels, Marc C, Zhou, Guangqian, Schalij, Martin J, Ypey, Dirk L, Pijnappels, Daniël A, de Vries, Antoine ...

Date : 01/12/2018 Item size : 388299 bytes
Ehjcardiovascrec

Introduction The RHOA-Rho kinase (ROCK1/2) signalling pathway is associated with multiple cardiovascular, metabolic, and neurodegenerative diseases, and cancer.1 RHOA is a member of a family of small ...

Cardiovascular Research, Vicente-Steijn, Rebecca, Kelder, Tim P., Tertoolen, Leon G., Wisse, Lambertus J., Pijnappels, Daniël A., Poelmann, Robert E., Schalij, Martin J., deRuiter, Marco C., ...

Date : 01/08/2017 Item size : 377050 bytes
Ehjcardiovascrec

Over decades of research, a vast amount of knowledge has been gathered about the causes and consequences of AF related to cellular electrophysiology and features of the tissue structure that ...

Cardiovascular Research, Opacic, Dragan, van Bragt, Kelly A., Nasrallah, Hussein M., Schotten, Ulrich, Verheule, Sander

Date : 01/04/2016 Item size : 864573 bytes
Ehjcardiovascrec

Emergent evidence suggests that CaMKII may play an important role in promoting atrial fibrillation (AF) by targeting a diverse array of proteins involved in membrane excitability, cell survival, ...

Cardiovascular Research, Mesubi, Olurotimi O., Anderson, Mark E.

Date : 01/04/2016 Item size : 953190 bytes
Ehjcardiovascrec

Commentary on ATP as a biological hydrotrope by Patel et al., Science 2017.1 Ageing and age-related diseases have long been associated with the accumulation of misfolded proteins and protein ...

Cardiovascular Research, Meyer, Thomas, Voigt, Niels

Date : 01/12/2017 Item size : 157098 bytes
Ehjcardiovascrec

Abstract Aims Human epicardial adipose tissue (EAT) is a visceral and perivascular fat that has been shown to act locally on myocardium, atria, and coronary arteries. Methods and results Samples of ...

Cardiovascular Research, Gaborit, Bénédicte, Venteclef, Nicolas, Ancel, Patricia, Pelloux, Véronique, Gariboldi, Vlad, Leprince, Pascal, Amour, Julien, Hatem, Stéphane N., Jouve, ...

Date : 01/10/2015 Item size : 425063 bytes
Ehjcardiovascrec

Nitro-fatty acids and possibly other lipid electrophiles thus emerge as potential therapeutic agents for AF, either by increasing endogenous levels through dietary modulation or by administration as ...

Cardiovascular Research, Rudolph, Tanja K., Ravekes, Thorben, Klinke, Anna, Friedrichs, Kai, Mollenhauer, Martin, Pekarova, Michaela, Ambrozova, Gabriela, Martiskova, Hana, Kaur, Jatinder-Jit, ...

Date : 01/01/2016 Item size : 327297 bytes