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Ehjcardiovascrec

Nishijima et al.1 recently published an article in Cardiovascular Research in which they described the effects of a treatment with the nitric oxide synthase (NOS) cofactor tetrahydrobiopterin (BH4) ...

Cardiovascular Research, Letter to the Editor, Harry J. Crijns, Ulrich Schotten, An L. Moens

Date : 01/08/2011 Item size : 135921 bytes
Ehjcardiovascrec

[...]Sp mice exhibited increased atrial ectopy and susceptibility to pacing-induced AF, both of which were also prevented by the RyR2 S2814A mutation. Previously, studies have found that protein ...

Cardiovascular Research, Ion channels and arrhythmias, David Y. Chiang, Na Li, Qiongling Wang, Katherina M. Alsina, Ann P. Quick, Julia O. Reynolds, Guoliang Wang, Darlene Skapura, Niels Voigt, ...

Date : 01/07/2014 Item size : 333015 bytes
Ehjcardiovascrec

The potential relevance of increased incidence of spontaneous SR Ca2+ release for both AF induction and/or maintenance and the development of novel mechanism-based therapeutic approaches will be ...

Cardiovascular Research, REVIEWS: FOCUS ON THE MOLECULAR BASIS OF ATRIAL FIBRILLATION, Dobromir Dobrev, Niels Voigt, Xander H.T. Wehrens

Date : 01/03/2011 Item size : 506157 bytes
Ehjcardiovascrec

In disease states, fibroblast production of increased quantities of ECM proteins leads to tissue fibrosis, which can impair both mechanical and electrical function of the heart, contributing to heart ...

Cardiovascular Research, REVIEWS: FOCUS ON THE MOLECULAR BASIS OF ATRIAL FIBRILLATION, Lixia Yue, Jia Xie, Stanley Nattel

Date : 01/03/2011 Item size : 519835 bytes
Ehjcardiovascrec

Here, we assessed the differential expression of Kv currents between atrial and ventricular fibroblasts from control dogs and dogs with an atrial arrhythmogenic substrate caused by congestive heart ...

Cardiovascular Research, Ion channels and arrhythmias, Chia-Tung Wu, Xiao-Yan Qi, Hai Huang, Patrice Naud, Kristin Dawson, Yung-Hsin Yeh, Masahide Harada, Chi-Tai Kuo, Stanley Nattel

Date : 01/06/2014 Item size : 319683 bytes
Ehjcardiovascrec

Abstract Aims The present study was designed to decipher molecular mechanisms underlying nicotine's promoting atrial fibrillation (AF) by inducing atrial structural remodelling. Introduction A large ...

Cardiovascular Research, Original Article, Hongli Shan, Yong Zhang, Yanjie Lu, Ying Zhang, Zhenwei Pan, Benzhi Cai, Ning Wang, Xuelian Li, Tieming Feng, Yuan Hong, Baofeng Yang

Date : 01/08/2009 Item size : 351172 bytes
Ehjcardiovascrec

Among the genes encoding the proteins underlying these currents, HERG codes for the K+ channel generating IKr, the target of class III antiarrhythmic drugs. Since this gene is also expressed at the ...

Cardiovascular Research, Editorial, Isabelle Baró

Date : 01/10/2006 Item size : 175784 bytes
Ehjcardiovascrec

Methods: Sterile pericarditis was created in 20 dogs randomly assigned to two groups: a control group (10 dogs) and an atorvastatin treatment group (10 dogs). On the second postoperative day, the ...

Cardiovascular Research, Original Article, Koichiro Kumagai, Hideko Nakashima, Keijiro Saku

Date : 01/04/2004 Item size : 245191 bytes
Ehjcardiovascrec

Introduction Nitric oxide (NO) synthetized by essentially all cardiac cell types is an ubiquitous cellular messenger that plays a key role in regulating cardiac function.15 NO is a highly diffusible ...

Cardiovascular Research, Review, Juan Tamargo, Ricardo Caballero, Ricardo Gómez, Eva Delpón

Date : 01/09/2010 Item size : 436503 bytes
Ehjcardiovascrec

The identification of the molecular structure of many ion channels involved in cardiac excitability and their functional correlation with native ionic currents have made it possible to study the ...

Cardiovascular Research, Review, Ralph F Bosch, Stanley Nattel

Date : 01/05/2002 Item size : 503601 bytes