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Abstract In the heart, changes in velocity and in patterns of conduction of myocardial electrical activity can affect cardiac rhythm and the coordination of contraction. Gap junctions are clusters ...

Cardiovascular Research, Review, Huub M.W van der Velden, Habo J Jongsma

Date : 01/05/2002 Item size : 372493 bytes

Introduction Atrial fibrillation (AF) is the most common cardiac arrhythmia, having a prevalence of 1% in young patients up to 9% in patients at the age of 75 years.1 It is estimated that the ...

Cardiovascular Research, REVIEWS: FOCUS ON THE MOLECULAR BASIS OF ATRIAL FIBRILLATION, Anne Margreet De Jong, Alexander H. Maass, Silke U. Oberdorf-Maass, Dirk J. Van Veldhuisen, Wiek H. Van Gilst, ...

Date : 01/03/2011 Item size : 631934 bytes

Results: Verapamil caused AF promotion in six dogs, increasing mean duration of AF induced by burst pacing, from 8±4 s (mean±S.E.) to 95±39 s (P<0.01 vs. control) at a loading dose of 0.1 ...

Cardiovascular Research, Original Article, Agnès Bénardeau, Samir Fareh, Stanley Nattel

Date : 01/04/2001 Item size : 252007 bytes

Introduction Experimental and clinical studies have established that atrial fibrillation (AF) induces a shortening of atrial refractoriness (electrical remodeling) [1,2]. If the relative ...

Cardiovascular Research, Original Article, M. Duytschaever, Y. Blaauw, M. Allessie

Date : 01/07/2005

Methods and results: 12 rabbit heart preparations were used to evaluate the ventricular rate during programmed regular high atrial rate pacing or random pacing from eight atrial sites. Conclusions: ...

Cardiovascular Research, Original Article, Stéphane Garrigue, Patrick J. Tchou, Todor N. Mazgalev

Date : 01/11/1999

Abstract Objective In electrically remodeled atria the effect of blockers of the delayed rectifier K+ current IKr on repolarization is reduced, whereas the efficacy of early class III drugs ...

Cardiovascular Research, Original Article, Y. Blaauw, U. Schotten, A. van Hunnik, H.R. Neuberger, M.A. Allessie

Date : 01/07/2007

For patients and physicians it remains frequently disabling, responsible for extra cost, morbidity and probably mortality, and often very frustrating [28]. The number of centers involved in a ...

Cardiovascular Research, Review, Pierre Jaïs, Rukshen Weerasooriya, Dipen C. Shah, Mélèze Hocini, Laurent Macle, Kee-Joon Choi, Christophe Scavee, Michel Haïssaguerre, Jacques Clémenty

Date : 01/05/2002

After a 5-day recovery period, rapid atrial pacing at 400 ppm was started, followed 2 days later by oral verapamil (8 mg/kg per day) in eight dogs (After group; A). [...]in B, these parameters did ...

Cardiovascular Research, Original Article, Yasuo Kurita, Hideo Mitamura, Akiko Shiroshita-Takeshita, Akiko Yamane, Masaki Ieda, Osamu Kinebuchi, Toshiaki Sato, Shunichiro Miyoshi, Motoki Hara, Seiji ...

Date : 01/05/2002

Abstract Background: AVE0118 (22-(4-Methoxy-phenyl)-acetylamino]-methyl}-biphenyl-2-carboxylic acid (2-pyridin-3-yl-ethyl)-amide) blocks atrial ultrarapid delayed rectifier currents (IKur) and ...

Cardiovascular Research, Rapid Communication, Ulrich Schotten, Sunniva de Haan, Sander Verheule, Erik G.A. Harks, Dirk Frechen, Eva Bodewig, Maura Greiser, Rashmi Ram, Jos Maessen, Malte Kelm, ...

Date : 01/01/2007

Introduction 1.1 Proteostasis The proper function of cells depends critically on the maintenance of a healthy homeostasis of protein expression, folding, assembly, trafficking, and degradation, ...

Cardiovascular Research, INVITED SPOTLIGHT REVIEWS, Deli Zhang, Xu Hu, Robert H. Henning, Bianca J.J.M. Brundel

Date : 01/04/2016