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The evolution of scientific knowledge has made the complex changes produced by cardiovascular disease sufficiently understood at the organ, cellular, and molecular levels such that there is a ...

Cardiovascular Research, Original Article

Date : 01/12/2001 Item size : 624034 bytes

Abstract Objective: The left human atrium plays an important role in initiation of atrial fibrillation (AF) and the hyperpolarization activated cation current (If) is a candidate for contributing to ...

Cardiovascular Research, Research Article, Klaus Zorn-Pauly, Peter Schaffer, Brigitte Pelzmann, Petra Lang, Heinrich Mächler, Bruno Rigler, Bernd Koidl

Date : 01/11/2004 Item size : 261977 bytes

[...]we suggest future studies designed to unravel the detailed molecular, cellular and pathophysiological mechanisms responsible for AF initiation and maintenance. Fibrillation, like flutter, may ...

Cardiovascular Research, Review, José Jalife, Omer Berenfeld, Moussa Mansour

Date : 01/05/2002 Item size : 381745 bytes

Results: Beat-to-beat variations in contractile function during atrial fibrillation in the patients were recorded as LVdP/dtmax and left ventricular ejection (ascending aortic) velocity integral ...

Cardiovascular Research, Original Article, Suzanna M.C Hardman, Mark I.M Noble, Tony Biggs, W.Anthony Seed

Date : 01/04/1998 Item size : 275972 bytes

[...]Na+ channel blockers with slow dissociation kinetics possess a clear propensity to provoke arrhythmias, in particular in patients with ischaemic heart disease.1 Proarrhythmic effects are also ...

Cardiovascular Research, Ion channels and arrhythmias, Erich Wettwer, Torsten Christ, Sebastian Endig, Nadiia Rozmaritsa, Klaus Matschke, Joseph J. Lynch, Marc Pourrier, John K. Gibson, David Fedida, ...

Date : 01/04/2013

Abstract Objective: Prolonged atrial fibrillation (AF) results in (ultra)structural remodelling of atrial cardiomyocytes resembling alterations seen in ischemia-induced ventricular hibernation. In ...

Cardiovascular Research, Original Article, Jannie Ausma, Will A Coumans, Hans Duimel, Ger J Van der Vusse, Maurits A Allessie, Marcel Borgers

Date : 01/09/2000

Abstract Objective: To determine whether INa and ICaL are altered in function/density in right atrial (RA) cells from dogs with chronic atrial fibrillation (cAF dogs, episodes lasting at least 6 ...

Cardiovascular Research, Original Article, Takuya Yagi, Jielin Pu, Parag Chandra, Motoki Hara, Peter Danilo, Michael R Rosen, Penelope A Boyden

Date : 01/05/2002

Abstract Objective: To investigate changes in human atrial single cell functional electrophysiological properties associated with chronic atrial fibrillation (AF), and the contribution to these of ...

Cardiovascular Research, Original Article, Antony J Workman, Kathleen A Kane, Andrew C Rankin

Date : 01/11/2001

Steady-state and nonsteady-state action potentials in fibrillating canine atrium: abnormal rate adaptation and its possible mechanisms Abstract Objective: Our goal was to study rate adaptation of ...

Cardiovascular Research, Original Article, Motoki Hara, Alexei Shvilkin, Michael R Rosen, Peter Danilo, Penelope A Boyden

Date : 01/05/1999

Special attention was paid to processing the tissues immediately (fixation/freezing) in order to prevent artificial degenerative changes, thereby excluding false positive identification of ...

Cardiovascular Research, Original Article, Gerrit D. Dispersyn, Jannie Ausma, Fred Thoné, Willem Flameng, Jean-Louis J. Vanoverschelde, Maurits A. Allessie, Frans C.S. Ramaekers, Marcel Borgers

Date : 01/09/1999