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Ehjcardiovascrec

The evolution of scientific knowledge has made the complex changes produced by cardiovascular disease sufficiently understood at the organ, cellular, and molecular levels such that there is a ...

Cardiovascular Research, Original Article

Date : 01/12/2001 Item size : 624034 bytes
Ehjcardiovascrec

Clinical and Regulatory Implications was held at the European Heart House in Sophia Antipolis, France, on the initiative of Günter Breithardt, FESC, FACC, on June 24th and 25th, 1999 after formal ...

Cardiovascular Research, Special article, Wilhelm Haverkamp, Günter Breithardt, A.John Camm, Michiel J Janse, Michael R Rosen, Charles Antzelevitch, Denis Escande, Michael Franz, Marek Malik, ...

Date : 01/08/2000 Item size : 431844 bytes
Ehjcardiovascrec

Introduction Nitric oxide (NO) synthetized by essentially all cardiac cell types is an ubiquitous cellular messenger that plays a key role in regulating cardiac function.15 NO is a highly diffusible ...

Cardiovascular Research, Review, Juan Tamargo, Ricardo Caballero, Ricardo Gómez, Eva Delpón

Date : 01/09/2010 Item size : 436503 bytes
Ehjcardiovascrec

The identification of the molecular structure of many ion channels involved in cardiac excitability and their functional correlation with native ionic currents have made it possible to study the ...

Cardiovascular Research, Review, Ralph F Bosch, Stanley Nattel

Date : 01/05/2002 Item size : 503601 bytes
Ehjcardiovascrec

Abstract Objectives: Although previous studies in dogs have indicated a minimal role for changes in IK1 in the shortening of action potential duration (APD) associated with atrial fibrillation (AF), ...

Cardiovascular Research, Original Article, Henggui Zhang, Clifford J. Garratt, Jiujiang Zhu, Arun V. Holden

Date : 01/06/2005
Ehjcardiovascrec

Atrial structural remodeling also occurs as a result of heart failure and other underlying cardiovascular diseases. The associated atrial fibrosis might explain intra-atrial conduction disturbances ...

Cardiovascular Research, Review, Maurits Allessie, Jannie Ausma, Ulrich Schotten

Date : 01/05/2002
Ehjcardiovascrec

Ion channels are the fundamental molecular units underlying cardiac electrophysiology, and it therefore follows that electrophysiologic remodeling represents alterations in the function or expression ...

Cardiovascular Research, Review, Dan M. Roden, Sabina Kupershmidt

Date : 01/05/1999
Ehjcardiovascrec

Atrial fibrillation (AF), the most common sustained arrhythmia, is associated with substantial cardiovascular morbidity and mortality, with stroke being the most critical complication.1 Present drugs ...

Cardiovascular Research, EDITORIAL: FOCUS ON THE MOLECULAR BASIS OF ATRIAL FIBRILLATION, Dobromir Dobrev, Stanley Nattel

Date : 01/03/2011
Ehjcardiovascrec

In atrial fibrillation (AF), the high atrial rate abbreviates the atrial action potential duration primarily by reduced ICa,L and increased inward-rectifier K+ currents like the background current ...

Cardiovascular Research, Dobrev, Dobromir, Wettwer, Erich

Date : 01/06/2008 Item size : 125314 bytes
Ehjcardiovascrec

Atrial fibrillation (AF), the most common sustained arrhythmia, is associated with substantial cardiovascular morbidity and mortality, with stroke being the most critical complication.1 Present drugs ...

Cardiovascular Research, Dobrev, Dobromir, Nattel, Stanley

Date : 01/03/2011 Item size : 158514 bytes