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Abstract Aims Previous studies showed that autonomic activation by high-frequency electrical stimulation (HFS) during myocardial refractoriness evokes rapid firing from pulmonary vein (PV) and atria, ...

Cardiovascular Research, Original Article, Zhibing Lu, Benjamin J. Scherlag, Jiaxiong Lin, Lilei Yu, Ji-Hong Guo, Guodong Niu, Warren M. Jackman, Ralph Lazzara, Hong Jiang, Sunny S. Po

Date : 01/11/2009 Item size : 260108 bytes

A substrate for atrial propensity to AF is required for AF initiation and maintenance. [...]we reviewed and discussed mainly the electrophysiological properties observed in ...

Cardiovascular Research, Review, Akihiko Shimizu, Osmar Antonio Centurion

Date : 01/05/2002 Item size : 533491 bytes

Abstract In the heart, changes in velocity and in patterns of conduction of myocardial electrical activity can affect cardiac rhythm and the coordination of contraction. Gap junctions are clusters ...

Cardiovascular Research, Review, Huub M.W van der Velden, Habo J Jongsma

Date : 01/05/2002 Item size : 372493 bytes

Methods and results: 12 rabbit heart preparations were used to evaluate the ventricular rate during programmed regular high atrial rate pacing or random pacing from eight atrial sites. Conclusions: ...

Cardiovascular Research, Original Article, Stéphane Garrigue, Patrick J. Tchou, Todor N. Mazgalev

Date : 01/11/1999

For patients and physicians it remains frequently disabling, responsible for extra cost, morbidity and probably mortality, and often very frustrating [28]. The number of centers involved in a ...

Cardiovascular Research, Review, Pierre Jaïs, Rukshen Weerasooriya, Dipen C. Shah, Mélèze Hocini, Laurent Macle, Kee-Joon Choi, Christophe Scavee, Michel Haïssaguerre, Jacques Clémenty

Date : 01/05/2002

Introduction Atrial fibrillation (AF) represents the most common rhythm disorder with a life-time risk for those reaching 40 years of age of 25% in Europe and the USA.1 This arrhythmia is associated ...

Cardiovascular Research, Original Article, Tanja K. Rudolph, Thorben Ravekes, Anna Klinke, Kai Friedrichs, Martin Mollenhauer, Michaela Pekarova, Gabriela Ambrozova, Hana Martiskova, Jatinder-Jit ...

Date : 01/01/2016

Abstract Objective: Although the incidence of atrial fibrillation (AF) increases with age, the cellular electrophysiological changes that render the atria of aged individuals more susceptible to AF ...

Cardiovascular Research, Original Article, Evgeny P. Anyukhovsky, Eugene A. Sosunov, Parag Chandra, Tove S. Rosen, Penelope A. Boyden, Peter Danilo, Michael R. Rosen

Date : 01/05/2005

[...]we tested the hypothesis that a rare stimulation pattern might alter the myocardial substrate, making it more susceptible to the initiation of arrhythmias. Methods: In isolated right and left ...

Cardiovascular Research, Original Article, Eugene A. Sosunov, Evgeny P. Anyukhovsky, David Hefer, Tove S. Rosen, Peter Danilo, Michiel J. Janse, Michael R. Rosen

Date : 01/08/2005

The ability to study the importance of a single gene product in pathophysiology make this a potentially powerful tool to understand the causal relationship of several proteins and the substrate for ...

Cardiovascular Research, Review, Jeffrey E. Olgin, Sander Verheule

Date : 01/05/2002

Abstract Objectives: AVE0118 is a novel blocker of the K+ channels Kv1.5 and Kv4.3 which are the molecular basis for the human cardiac ultrarapid delayed rectifier potassium current (IKur) and the ...

Cardiovascular Research, Original Article, Klaus J Wirth, Tobias Paehler, Bjoern Rosenstein, Karsten Knobloch, Thomas Maier, Jennifer Frenzel, Joachim Brendel, Andreas E Busch, Markus Bleich

Date : 01/11/2003