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Future research for validation and improvement of current clinical electrophysiology mapping technologies will be crucial for developing mechanistic-based selection and application of the best ...

Cardiovascular Research, INVITED SPOTLIGHT REVIEWS, María S. Guillem, Andreu M. Climent, Miguel Rodrigo, Francisco Fernández-Avilés, Felipe Atienza, Omer Berenfeld

Date : 01/04/2016 Item size : 531353 bytes

Abstract Objectives: The expression and distribution of connexins is abnormal in a number of cardiac diseases, including atrial fibrillation, and is believed to favor conduction slowing and ...

Cardiovascular Research, Original Article, Catherine Rucker-Martin, Paul Milliez, Sisareuth Tan, Xavier Decrouy, Michel Recouvreur, Roger Vranckx, Claude Delcayre, Jean-François Renaud, Irene ...

Date : 01/10/2006 Item size : 317530 bytes

Furthermore, studies in humans suggest a protective role for HSPs against progression from paroxysmal AF to chronic, persistent AF. [...]manipulation of the HSP system may offer novel therapeutic ...

Cardiovascular Research, Review, Bianca J.J.M. Brundel, Lei Ke, Anne-Jan Dijkhuis, XiaoYan Qi, Akiko Shiroshita-Takeshita, Stanley Nattel, Robert H. Henning, Harm H. Kampinga

Date : 01/06/2008 Item size : 448399 bytes

Abstract Background: The L-type calcium channel (LCC) plays a crucial role in the electrical remodeling of atrial fibrillation (AF). [...]we performed a single LCC analysis to assess channel gating ...

Cardiovascular Research, Original Article, Gunnar Klein, Frank Schröder, David Vogler, Arnd Schaefer, Axel Haverich, Bernhard Schieffer, Thomas Korte, Helmut Drexler

Date : 01/07/2003 Item size : 239221 bytes

The prevalence of AF has been increasing, due to both ageing of the population and an increased prevalence of risk factors such as obesity and sedentary lifestyle. Many of the available ...

Cardiovascular Research, Editorial, David R. Van Wagoner

Date : 01/04/2013 Item size : 162016 bytes

A substrate for atrial propensity to AF is required for AF initiation and maintenance. [...]we reviewed and discussed mainly the electrophysiological properties observed in ...

Cardiovascular Research, Review, Akihiko Shimizu, Osmar Antonio Centurion

Date : 01/05/2002 Item size : 533491 bytes

Calpain activity correlated with L-type Ca2+ channel and Kv1.5 protein amounts (r=0.80, P<0.001 and r=0.72, P<0.001, respectively), degree of structural changes (r=0.90, P<0.001), shortening of ...

Cardiovascular Research, Original Article, Bianca J.J.M Brundel, Jannie Ausma, Isabelle C van Gelder, Johan J.L Van Der Want, Wiek H van Gilst, Harry J.G.M Crijns, Robert H Henning

Date : 01/05/2002 Item size : 282302 bytes

Whether this also holds for patients with chronic heart failure is at present unsettled, but obviously, these patients would benefit most from sinus rhythm since with restoration and maintenance of ...

Cardiovascular Research, Editorial, Isabelle C. Van Gelder

Date : 01/04/2007 Item size : 171177 bytes

Introduction Atrial fibrillation (AF) is the most common cardiac arrhythmia, having a prevalence of 1% in young patients up to 9% in patients at the age of 75 years.1 It is estimated that the ...

Cardiovascular Research, REVIEWS: FOCUS ON THE MOLECULAR BASIS OF ATRIAL FIBRILLATION, Anne Margreet De Jong, Alexander H. Maass, Silke U. Oberdorf-Maass, Dirk J. Van Veldhuisen, Wiek H. Van Gilst, ...

Date : 01/03/2011 Item size : 631934 bytes

Introduction Experimental and clinical studies have established that atrial fibrillation (AF) induces a shortening of atrial refractoriness (electrical remodeling) [1,2]. If the relative ...

Cardiovascular Research, Original Article, M. Duytschaever, Y. Blaauw, M. Allessie

Date : 01/07/2005