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In the present studies, eprosartan's ability to provide end-organ protection was evaluated in a model of cardiomyopathy and renal failure in stroke-prone rats (SP). Echocardiographic (i.e. 2-D ...

Cardiovascular Research, Original Article, Frank C. Barone, Robert W. Coatney, Sudeep Chandra, Susanta K. Sarkar, Allen H. Nelson, Lisa C. Contino, David P. Brooks, Wallace G. Campbell, Eliot H. ...

Date : 01/06/2001 Item size : 322347 bytes

Abstract Aims Diabetic cardiomyopathy is characterized by the production of a disorganized fibrotic matrix in the absence of coronary atherosclerosis and hypertension. Introduction Diabetic ...

Cardiovascular Research, Original Article, Ilana Talior-Volodarsky, Kim A. Connelly, Pamma D. Arora, Donald Gullberg, Christopher A. McCulloch

Date : 01/11/2012 Item size : 363435 bytes

Abstract Objective: To assess the long-term efficacy of vasopressin (AVP) V1a and V2 receptor blockade with conivaptan, alone and in combination with angiotensin converting enzyme (ACE) inhibition on ...

Cardiovascular Research, Original Article, Mareo Naitoh, John Risvanis, Leanne C. Balding, Colin I. Johnston, Louise M. Burrell

Date : 01/04/2002 Item size : 257113 bytes

[...]the chymase dAIIFA of internal thoracic arteries obtained from coronary bypass operations correlated positively with serum low-density lipoprotein (LDL)-cholesterol levels [9]. [...]the ...

Cardiovascular Research, Original Article, Yoshinari Uehara, Hidenori Urata, Munehito Ideishi, Kikuo Arakawa, Keijiro Saku

Date : 01/09/2002 Item size : 230939 bytes

Vascular smooth muscle cells from IκBNS mice showed a significant increase in cell migration compared with those from IκBNS+/+ mice after IL-6 stimulation in the scratch-wound healing ...

Cardiovascular Research, Original Article, Tomiharu Niida, Kikuo Isoda, Manabu Kitagaki, Norio Ishigami, Takeshi Adachi, Osamu Matsubara, Kiyoshi Takeda, Tadamitsu Kishimoto, Fumitaka Ohsuzu

Date : 01/02/2012 Item size : 301903 bytes

Introduction The prevalence and mortality rate of heart failure dramatically increase in older people, and ageing is one of the risk factors for cardiovascular events.1 With ageing, the heart shows ...

Cardiovascular Research, Cardiac biology and remodelling, Tomofumi Misaka, Satoshi Suzuki, Makiko Miyata, Atsushi Kobayashi, Tetsuro Shishido, Akihito Ishigami, Shu-ichi Saitoh, Masamichi Hirose, ...

Date : 01/08/2013

Abstract Aims We determined the role of the Rho kinase (ROCK) isoforms in diabetes-induced vascular endothelial dysfunction and enhancement of arginase activity and expression. Introduction In ...

Cardiovascular Research, Original Article, Lin Yao, Surabhi Chandra, Haroldo A. Toque, Anil Bhatta, Modesto Rojas, Ruth B. Caldwell, R. William Caldwell

Date : 01/03/2013

Several risk factors modify the progression of hypertrophy, the associated progressive impairment of myocardial function, and eventually the transition to overt congestive heart failure. Endpoints ...

Cardiovascular Research, Original Article, K. Meurrens, S. Ruf, G. Ross, R. Schleef, K. von Holt, K.-D. Schlüter

Date : 01/11/2007

Abstract Objective: This study investigated whether endothelial dysfunction occurs in mesenteric arteries of apoE-deficient mice and determined the role of endothelin (ET)-1, which is increased in ...

Cardiovascular Research, Original Article, Livius V d'Uscio, Matthias Barton, Sidney Shaw, Thomas F Lüscher

Date : 01/02/2002

Methods 2.1 Animals Transgenic mice with human CRP expression (CRPTG, C57BL/6 background) were generated under direction of the CAG promoter to induce ubiquitous transgene expression.7 Male CRPTG at ...

Cardiovascular Research, Original Article, Hidehiro Kaneko, Toshihisa Anzai, Toshiyuki Nagai, Atsushi Anzai, Toshiyuki Takahashi, Yoshinori Mano, Kohkichi Morimoto, Yuichiro Maekawa, Hiroshi Itoh, ...

Date : 01/08/2011