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Through the metabolic breakdown of ingested nutrients, subsequent production of the electron carriers NADH and FADH2 in the citric acid cycle and the transfer of electrons through the electron ...

Cardiovascular Research, Review, Alexander W. Lohman, Marie Billaud, Brant E. Isakson

Date : 01/08/2012 Item size : 637634 bytes

An ideal animal model for any cardiovascular disease in humans should have five characteristics: (i) mimic the human disease, (ii) allow studies in chronic, stable disease, (iii) produce symptoms ...

Cardiovascular Research, Review, Sheila A Doggrell, Lindsay Brown

Date : 01/07/1998 Item size : 693819 bytes

In addition to the well known difference in age of presentation of coronary heart disease, women are more likely to suffer from Raynaud's phenomenon, and to experience presyncopal or syncopal ...

Cardiovascular Research, Review, Anthony M Dart, Xiao-Jun Du, Bronwyn A Kingwell

Date : 15/02/2002 Item size : 534345 bytes

The goal of this review is to summarize the available information regarding the mechanism whereby PI3Kγ exerts blood pressure control, regulating myogenic tone at the level of L-type calcium ...

Cardiovascular Research, Review, Daniela Carnevale, Giuseppe Lembo

Date : 01/09/2012 Item size : 308134 bytes

Abstract Endothelial production of nitric oxide (nitrogen monoxide, NO) has become a major research area in vascular biology. The aim of this review is to examine the cellular and molecular ...

Cardiovascular Research, Review, Michael T Gewaltig, Georg Kojda

Date : 01/08/2002 Item size : 486616 bytes

Abstract Objective: This study is aimed to explore whether gender plays a role in the generation of nitric oxide (NO) and superoxide anion (O2 in microvessels of hypertensive rats (SHR), as well as ...

Cardiovascular Research, Original Article, Ana Paula V Dantas, Maria do Carmo P Franco, Michele M Silva-Antonialli, Rita C.A Tostes, Zuleica B Fortes, Dorothy Nigro, Maria Helena C Carvalho

Date : 01/01/2004 Item size : 252323 bytes

Abstract Aims The aim of the study is to investigate transient receptor potential ankyrin 1 (TRPA1)-induced responses in the vasculature and on blood pressure and heart rate (HR), in response to ...

Cardiovascular Research, Original Article, Gabor Pozsgai, Jennifer V. Bodkin, Rabea Graepel, Stuart Bevan, David A. Andersson, Susan D. Brain

Date : 01/09/2010 Item size : 305575 bytes

Abstract Diseases such as hypertension, atherosclerosis and diabetes are associated with vascular functional and structural changes including endothelial dysfunction, altered contractility and ...

Cardiovascular Research, Review, Tamara M. Paravicini, Rhian M. Touyz

Date : 15/07/2006 Item size : 519535 bytes

Abstract Aim The effects of nitric oxide (NO) in the cardiovascular system are attributed in part to cGMP synthesis by the α1β1 isoform of soluble guanylate cyclase (sGC). Because available ...

Cardiovascular Research, Original Article, Emmanuel S. Buys, Patrick Sips, Pieter Vermeersch, Michael J. Raher, Elke Rogge, Fumito Ichinose, Mieke Dewerchin, Kenneth D. Bloch, Stefan Janssens, Peter ...

Date : 01/07/2008

Abstract Objective: Studies show general agreement that all-trans retinoic acid (atRA) has been linked to the regulation of G protein-coupled receptor (GPCRs) signaling. Methods: Real-time ...

Cardiovascular Research, Research Article, Jiu-Chang Zhong, Dong-Yang Huang, Ge-Fei Liu, Hai-Yan Jin, Yan-Mei Yang, Yi-Fan Li, Xu-Hong Song, Kun Du

Date : 15/02/2005