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Vascular smooth muscle cells (VSMCs) are the stromal cells of the vascular wall, and, due to their myosin/actin interactions, they are also responsible for arterial contractile tonus and regulating ...

Cardiovascular Research, Editorial, Jean-Baptiste Michel, Zhenlin Li, Patrick Lacolley

Date : 15/07/2012 Item size : 189309 bytes

Abstract Objective: This study is aimed to explore whether gender plays a role in the generation of nitric oxide (NO) and superoxide anion (O2 in microvessels of hypertensive rats (SHR), as well as ...

Cardiovascular Research, Original Article, Ana Paula V Dantas, Maria do Carmo P Franco, Michele M Silva-Antonialli, Rita C.A Tostes, Zuleica B Fortes, Dorothy Nigro, Maria Helena C Carvalho

Date : 01/01/2004 Item size : 252323 bytes

Abstract Objective: To study the effect of pioglitazone (a PPAR gamma agonist) treatment on blood pressure, endothelial function, and oxidative stress in streptozotocin (STZ)-induced diabetic ...

Cardiovascular Research, Original Article, Jayesh B. Majithiya, Arvind N. Paramar, R. Balaraman

Date : 01/04/2005 Item size : 343088 bytes

Abstract Diseases such as hypertension, atherosclerosis and diabetes are associated with vascular functional and structural changes including endothelial dysfunction, altered contractility and ...

Cardiovascular Research, Review, Tamara M. Paravicini, Rhian M. Touyz

Date : 15/07/2006 Item size : 519535 bytes

Overexpression of PKCβ2 is associated with increased expression of connective tissue growth factor (CTGF) in myocardium, resulting in myocardial hypertrophy. Introduction Evidence suggests that ...

Cardiovascular Research, Original Article, Zhengyuan Xia, Kuo-Hsing Kuo, Prabhakara R. Nagareddy, Fang Wang, Zhixin Guo, Tianhai Guo, Jihong Jiang, John H. McNeill

Date : 01/03/2007

Introduction The prevalence and mortality rate of heart failure dramatically increase in older people, and ageing is one of the risk factors for cardiovascular events.1 With ageing, the heart shows ...

Cardiovascular Research, Cardiac biology and remodelling, Tomofumi Misaka, Satoshi Suzuki, Makiko Miyata, Atsushi Kobayashi, Tetsuro Shishido, Akihito Ishigami, Shu-ichi Saitoh, Masamichi Hirose, ...

Date : 01/08/2013

Abstract Objective: Pressure-induced vasodilation (PIV) allows skin blood flow to increase in response to locally applied pressure and may be protective against pressure ulcers. Conclusions: LPA ...

Cardiovascular Research, Original Article, Claire Demiot, Bérengère Fromy, Jean Louis Saumet, Dominique Sigaudo-Roussel

Date : 01/01/2006

Abstract Aims Oxidative stress followed by abnormal signalling can play a critical role in the development of long-term, high blood pressure-induced cardiac remodelling in heart failure (HF). Since ...

Cardiovascular Research, Original Article, Eva Bartha, Izabella Solti, Laszlo Kereskai, Janos Lantos, Eniko Plozer, Klara Magyar, Eszter Szabados, Tamás Kálai, Kálmán Hideg, Robert ...

Date : 01/08/2009

In cultured cardiomyocytes, adenoviral overexpression of Nrf2 shRNA enhanced Ang II-induced reactive oxygen species (ROS) production and protein synthesis, whereas adenoviral overexpression of Nrf2 ...

Cardiovascular Research, Original Article, Jinqing Li, Cheng Zhang, Yifan Xing, Joseph S. Janicki, Masayuki Yamamoto, Xing Li Wang, Dong-Qi Tang, Taixing Cui

Date : 01/05/2011

Histone deacetylase (HDAC)-1 recruitment and H3 histone acetylation at the eNOS promoter were elevated and diminished, respectively, in DJ-1/park7 mice compared with DJ-1/park7+/+ controls. [...]SBP ...

Cardiovascular Research, Vascular biology, Kyung Jong Won, Seung Hyo Jung, Soo Hyun Jung, Kang Pa Lee, Hwan Myung Lee, Dong-Youb Lee, Eun-Seok Park, Junghwan Kim, Bokyung Kim

Date : 01/03/2014