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In the present studies, eprosartan's ability to provide end-organ protection was evaluated in a model of cardiomyopathy and renal failure in stroke-prone rats (SP). Echocardiographic (i.e. 2-D ...

Cardiovascular Research, Original Article, Frank C. Barone, Robert W. Coatney, Sudeep Chandra, Susanta K. Sarkar, Allen H. Nelson, Lisa C. Contino, David P. Brooks, Wallace G. Campbell, Eliot H. ...

Date : 01/06/2001 Item size : 322347 bytes

Abstract Objective: This study is aimed to explore whether gender plays a role in the generation of nitric oxide (NO) and superoxide anion (O2 in microvessels of hypertensive rats (SHR), as well as ...

Cardiovascular Research, Original Article, Ana Paula V Dantas, Maria do Carmo P Franco, Michele M Silva-Antonialli, Rita C.A Tostes, Zuleica B Fortes, Dorothy Nigro, Maria Helena C Carvalho

Date : 01/01/2004 Item size : 252323 bytes

Results: Following haemorrhage mean arterial pressure (MAP) fell by 2545 mm Hg and was accompanied by a reduction in mesenteric BF without any alteration of mesenteric vascular conductance ...

Cardiovascular Research, Original Article, Doris Pieber, Gabi Horina, Andreas Sandner-Kiesling, Thomas R. Pieber, Akos Heinemann

Date : 01/10/1999 Item size : 268272 bytes

Abstract Aims The aim of the study is to investigate transient receptor potential ankyrin 1 (TRPA1)-induced responses in the vasculature and on blood pressure and heart rate (HR), in response to ...

Cardiovascular Research, Original Article, Gabor Pozsgai, Jennifer V. Bodkin, Rabea Graepel, Stuart Bevan, David A. Andersson, Susan D. Brain

Date : 01/09/2010 Item size : 305575 bytes

The total number of ventricular ectopic beats (VEB's) were counted and expressed as median (Q1Q3) and the incidence of ventricular fibrillation (VF) and ventricular tachycardia (VT) in each group was ...

Cardiovascular Research, Original Article, Isam Sharif, Kathleen A. Kane, Cherry L. Wainwright

Date : 01/09/1998

The TRPV1-mediated vasodilatation was also attenuated by treatment with superoxide dismutase and the hydrogen peroxide scavenger catalase, but not by deactivated enzymes, supporting a novel role for ...

Cardiovascular Research, Original Article, Anna Starr, Rabea Graepel, Julie Keeble, Sabine Schmidhuber, Natalie Clark, Andrew Grant, Ajay M. Shah, Susan D. Brain

Date : 01/04/2008

Methods: Using local intra-arterial administration of losartan, a selective angiotensin II type 1 (AT1) receptor antagonist, we examined the contribution of endogenous angiotensin II to the ...

Cardiovascular Research, Original Article, David E Newby, Satoko Masumori, Neil R Johnston, Nicholas A Boon, David J Webb

Date : 01/11/1997

Angiotensin II induced a 8.6±2.1-fold increase in cysteinyl leukotriene production in aorta rings from SHR with endothelium which was prevented by the AT1 receptor antagonist losartan 1 μM but ...

Cardiovascular Research, Original Article, Françoise Stanke-Labesque, Philippe Devillier, Sophie Veitl, Françoise Caron, Jean-Luc Cracowski, Germain Bessard

Date : 01/01/2001

KeywordsBlood pressureEndothelinsHypertensionReceptorsTime for primary review 23 days. 1 Introduction The potent vasoconstrictor endothelin (ET)-1 can play an important pathogenic role in arterial ...

Cardiovascular Research, Original Article, Gian Paolo Rossi, Chiara Ganzaroli, Maurizio Cesari, Andrea Maresca, Mario Plebani, Gastone G. Nussdorfer, Achille C. Pessina

Date : 01/01/2003

[...]when studying in vivo vascular responses in man, systemically administered agents can cause effects on other organ systems, such as the liver, brain, kidney and heart, and influence neurohumoral ...

Cardiovascular Research, Original Article, David Ernest Newby, Rajiv Jalan, Satoko Masumori, Peter Clive Hayes, Nicholas Antony Boon, David John Webb

Date : 01/04/1998