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Abstract Objective: To assess the long-term efficacy of vasopressin (AVP) V1a and V2 receptor blockade with conivaptan, alone and in combination with angiotensin converting enzyme (ACE) inhibition on ...

Cardiovascular Research, Original Article, Mareo Naitoh, John Risvanis, Leanne C. Balding, Colin I. Johnston, Louise M. Burrell

Date : 01/04/2002 Item size : 257113 bytes

Abstract Aims Sustained hypertension leads to cardiac hypertrophy that can progress, through pathological remodelling, to heart failure. Conclusion Low-level local AT1R activity in differentiated ...

Cardiovascular Research, Original Article, Justin F.X. Ainscough, Mark J. Drinkhill, Alicia Sedo, Neil A. Turner, David A. Brooke, Anthony J. Balmforth, Stephen G. Ball

Date : 15/02/2009

Since Ang II is a pleiotropic peptide, the age-protecting effects of RAS blockade are expected to involve a variety of other mechanisms. Caloric restriction (CR)an age-retarding intervention in ...

Cardiovascular Research, Review, Elena M.V. de Cavanagh, Felipe Inserra, León Ferder

Date : 01/01/2011

KeywordsBlood pressureHypertensionHypertrophyRenal function 1 Introduction From the 1940s to the late 1960s, The Cleveland Clinic Foundation's Division of Research was a hub of advanced laboratory ...

Cardiovascular Research, Historical note, Subha Sen

Date : 01/01/2000

Abstract Objective: A large number of clinical and experimental studies supports the hypothesis that intrauterine undernutrition is an important determinant of hypertension, coronary heart disease ...

Cardiovascular Research, Review, Maria do Carmo Pinho Franco, Dorothy Nigro, Zuleica B Fortes, Rita C.A Tostes, Maria Helena C Carvalho, Sandra Regina Rodrigues Lucas, Guiomar Nascimento Gomes, ...

Date : 01/11/2003

Abstract Objective: Reninangiotensin system (RAS) activation leads to increased production of NAD(P)H oxidase-derived reactive oxygen species (ROS), and both have been implicated in the initiation ...

Cardiovascular Research, Original Article, Karsten Grote, Magdalene Ortmann, Gustavo Salguero, Carola Doerries, Ulf Landmesser, Maren Luchtefeld, Ralf P. Brandes, Wilfried Gwinner, Thomas Tschernig, ...

Date : 01/08/2006

[...]the timing of initiation of treatment has not been fully elucidated. [...]the purpose of the present study was to compare the effects of very early (30 min after MI), early (3 and 24 h after ...

Cardiovascular Research, Original Article, Qin-Gui Xia, Oliver Chung, Heidi Spitznagel, Sascha Illner, Gunnar Jänichen, Birthe Rossius, Peter Gohlke, Thomas Unger

Date : 01/01/2001

Abstract Objective: Polymorphisms in several genes of the reninangiotensin system have been implicated as risk factors for myocardial infarction and ischaemic heart disease. The aim of this study ...

Cardiovascular Research, Original Article, Gillian I. Rice, Carole A. Foy, Peter J. Grant

Date : 01/03/1999

Currently diuretics (e.g. thiazides), beta-receptor antagonists, calcium channel blockers, alpha-receptor antagonists, and angiotensin-converting enzyme (ACE) inhibitors are commonly used for the ...

Cardiovascular Research, Editorial, László Dézsi

Date : 01/09/2000

Abstract Objective: to examine the association between coronary artery disease and polymorphisms at the angiotensin-converting enzyme (ACE) and angiotensin II type 1 receptor (AT1R) genes. Methods: ...

Cardiovascular Research, Original Article, Ruth Álvarez, Julián R Reguero, Alberto Batalla, Gustavo Iglesias-Cubero, Arturo Cortina, Victoria Álvarez, Eliecer Coto

Date : 01/11/1998