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An ideal animal model for any cardiovascular disease in humans should have five characteristics: (i) mimic the human disease, (ii) allow studies in chronic, stable disease, (iii) produce symptoms ...

Cardiovascular Research, Review, Sheila A Doggrell, Lindsay Brown

Date : 01/07/1998 Item size : 693819 bytes

Methods and results We used spectral analysis of systolic blood pressure (SBP) variability in mice chronically equipped with telemetry implants to identify frequency ranges (0.050.4 Hz; very low ...

Cardiovascular Research, Original Article, Fanny Desjardins, Irina Lobysheva, Michel Pelat, Bernard Gallez, Olivier Feron, Chantal Dessy, Jean-Luc Balligand

Date : 01/08/2008 Item size : 271138 bytes

Effect of respiratory rate on the relationships between RR interval and systolic blood pressure fluctuations: a frequency-dependent phenomenon Abstract Objective: The aims of this study were to ...

Cardiovascular Research, Original Article, Maria Vittoria Pitzalis, Filippo Mastropasqua, Francesco Massari, Andrea Passantino, Roberto Colombo, Antonella Mannarini, Cinzia Forleo, Paolo Rizzon

Date : 01/05/1998 Item size : 250213 bytes

In addition to the well known difference in age of presentation of coronary heart disease, women are more likely to suffer from Raynaud's phenomenon, and to experience presyncopal or syncopal ...

Cardiovascular Research, Review, Anthony M Dart, Xiao-Jun Du, Bronwyn A Kingwell

Date : 15/02/2002 Item size : 534345 bytes

Here we describe the natural history of ventricular hypertrophy and fibrosis in the transgenic (mRen2)27 rat a monogenetic model which has a high tissue expression of the murine renin transgene, and ...

Cardiovascular Research, Original Article, Jill E. Bishop, Linda A. Kiernan, Hugh E. Montgomery, Peter Gohlke, Jean R. McEwan

Date : 01/07/2000 Item size : 254674 bytes

Abstract Aims Previously we confirmed an important role of rat chromosome 19 (RNO19) for salt-sensitive hypertension and target organ damage in male Dahl salt-sensitive rats (SS rats). The aim of ...

Cardiovascular Research, Original Article, Norbert Wendt, Angela Schulz, Fatimunnisa Qadri, Juliane Bolbrinker, Peter Kossmehl, Karl Winkler, Monika Stoll, Roland Vetter, Reinhold Kreutz

Date : 15/02/2009 Item size : 236296 bytes

Abstract Objectives: To determine the effects of calcium antagonists on hyperinsulinemia, hypertriglyceridemia and hypertension, we examined the long-term effects of a new calcium channel blocker, ...

Cardiovascular Research, Original Article, Subodh Verma, Sanjay Bhanot, Alan Hicke, John H McNeill

Date : 01/04/1997 Item size : 188577 bytes

Methods: Ischemia was induced in the hindlimb of SHR by excision of the femoral artery, after which the animals were randomly assigned to receive low-dose perindopril (sub-antihypertensive, 0.2 ...

Cardiovascular Research, Original Article, Satoshi Takeshita, Hirofumi Tomiyama, Naoyuki Yokoyama, Yutaka Kawamura, Taiji Furukawa, Yutaka Ishigai, Toshiro Shibano, Takaaki Isshiki, Tomohide Sato

Date : 01/11/2001

Abstract Objective: A relative hyperadrenergic tone related to abnormalities of the autonomic nervous system is suspected in the mechanisms of sudden death. [...]we assessed the role of an elevated ...

Cardiovascular Research, Original Article, Xavier Jouven, Mahmoud Zureik, Michel Desnos, Claude Guérot, Pierre Ducimetière

Date : 01/05/2001

Results: Both medications prevented left ventricular systolic dysfunction and enlargement at age 31 weeks, and attenuated macrophage infiltration, reactive oxygen species generation, and ...

Cardiovascular Research, Original Article, Junichi Yoshida, Kazuhiro Yamamoto, Toshiaki Mano, Yasushi Sakata, Mayu Nishio, Tomohito Ohtani, Masatsugu Hori, Takeshi Miwa, Tohru Masuyama

Date : 01/10/2005